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Acevor (Roxithromycin)
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Acevor

Acevor is an antibiotic that is used to treat infections such as infections of the chest, tonsils, skin or genitals. It works by killing or stopping the growth of bacteria (bugs). Like all antibiotics, Acevor is not effective against infections caused by viruses.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Assoral, Azuril, Biaxsig, Bicofen, Claramid, Elrox, Infectoroxit, Klomicina, Macrolid, Makrodex, Nirox, Odonticina, Pedilid, Pedrox, Redotrin, Remora, Ritosin, Rokilide, Roksolit, Rolexit, Rolicyn, Romac, Rotramin, Roxithromycin, Roxithromycinum, Roxitromicina

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Also known as: Roxithromycin

Description

Each Acevor tablet contains either 150mg or 300mg of the active ingredient roxithromycin. Each tablet also contains: hydroxypropylcellulose, poloxamer, povidone, colloidal anhydrous silica, magnesium stearate (470), purified talc (553), maize starch, hypromellose, anhydrous glucose, titanium dioxide (171), propylene glycol (1520). Acevor does not contain gluten, sucrose, lactose, tartrazine or any other azo dyes.

Dosage

Acevor is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.

Overdose

Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.

Storage

Keep the tablets in the foil until it is time to take them.

Keep the tablets/in a cool dry place where the temperature stays below 30 degrees C.

Do not store Acevor or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Acevor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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Fixation stability was compared in an axial load-to-failure model. This study investigated the effect of the pre- and perinatal exposure to di-(2-ethylhexyl) phthalate (DEHP) on the neuroendocrine parameters that regulate reproduction in peripubertal male rats. The findings suggest that cycling exercise results in decreased baseline activity of facial muscles involved in the expression of emotion but does not lead to changes in appetitive or defensive responses to emotional stimuli. Effects of sulfatide and its precursor galactosylceramide (gal-cer) on the kinetics of production of cytokines were studied. Telehealth is an important resource for the Alaskan healthcare system, which is tasked with providing services to culturally diverse populations living in remote areas. Gas chromatographic-mass spectrometric identification and quantitation of benzyl alcohol from human serum and postmortem blood after derivatization with 4-carbethoxy hexafluorobutyryl chloride: a novel derivative. High signal abnormalities were widespread across AD, VaD and FTD. Community-based referrals for electrodiagnostic studies in patients with possible carpal tunnel syndrome: what is the diagnosis?. The only contraindications to surgery are the presence of extrahepatic metastases (with the exception of resectable lung metastases) and if radical removal of all detectable tumors is not possible. This article addresses the imaging appearances following endovascular abdominal aortic aneurysm repair (EVAR).

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The purpose of this study is to describe optical coherence tomography angiography (OCTA) flow characteristics and artifacts that might help to distinguish SHRM subtypes. The prevalence of 16 chronic conditions obtained at HF diagnosis classified into three groups: cardiovascular (CV) related, other physical, and mental. Forty-two consecutive subjects suffering from idiopathic PD (mild-to-moderate severity) with/without falls in the previous year were included. Safety and efficacy of preoperative induction therapy using a single high dose ATG-F in renal transplantation: a meta-analysis of randomized controlled trials. Most of the predicted intertype epitopes of HAdV hexon wer e exclusively found in synthetic peptides and recombinant proteins. Protein sequencing verified original spot identifications and extended the range of identified proteins. Is knee joint proprioception worse in the arthritic knee versus the unaffected knee in unilateral knee osteoarthritis?. We also describe the concept of fluorescent recovery after photobleaching (FRAP) and how it can be used to obtain information about HIV RNA transcription dynamics in living cells. To prevent serious morbidity and mortality, early diagnosis is essential.

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