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Actical (Calcitriol)
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Actical

Actical is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Actical is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Alfabond, Alfacal, Apcical, Arachitol, Arcium, Bonetuf, Calbec, Calbovic, Calcigra, Calcitriol, Caldix, Calfa, Calgel, Calotec, Calsure, Caltive, Caltop, Calzem, Carcal, Cholical, Dmcal, Duracal, Ikmag, Koncal, Kurecal, Novadee, Osteobel, Ostonex, Ostriol, Refirm, Rical, Ritoca, Roical, Rolsical, Solbiocal, Sorvate, Tobalt, Trolec, Vezocal, Vitalpha, Zaxial

Similar Products:
Adipex, Cardura, Imdur, Moduretic, Cytoxan, Analar, Alzil, Zyprinol, Ramigamma, Soztram, Amvik, Sycet, Baclofen, Celib, Acuvin,

Also known as: Calcitriol

Description

Generic Actical is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Actical are intestine and bone. Generic Actical receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Actical may also act on the kidney and the parathyroid glands. Generic Actical is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Actical has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Actical, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Actical in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Actical produces other independent beneficial effects. Actical is also known as Calcitriol. Generic Actical treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Actical is Calcitriol. Brand name of Generic Actical is Actical.

Dosage

Generic Actical is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Actical suddenly.

Overdose

If you overdose Generic Actical and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Actical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Actical if you are allergic to Generic Actical components. Do not take Generic Actical if you are pregnant, planning to become pregnant, or are breast-feeding. It is not known if this medication appears in breast milk. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Be careful with Generic Actical if you have heart disease, kidney disease or kidney stones, coronary artery disease (hardening of the arteries). Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. It can be dangerous to stop Generic Actical taking suddenly.

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