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Adplatt (Clopidogrel)
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Adplatt

Adplatt is a cheap, generically available blood thinner that prevents heart attack and stroke. For most patients, the typical dose of Adplatt is 75 mg by mouth once daily.

Other names for this medication:
Anticog, Asogrel, Blothin, Carpigrel, Ceruvin, Clofre, Clolyse, Clopicure, Clopidogrel, Clopisa, Clopivas, Cloplat, Clopod, Clospir, Clotnil, Compivas, Deplatt, Ecosprin, Livigrel, Noklot, Orawis, Plagril, Platfrin, Plodrel, Psygrel, Stagrel, Synplatt, Torplatt, Welgrel, Zeter, Zoclop, Zogrell

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Also known as: Clopidogrel

Description

Adplatt (clopidogrel) prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery.

Adplatt is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain (angina), or circulation problems.

Dosage

Usual Adult Dose for Acute Coronary Syndrome:

Unstable Angina (UA)/Non-ST-Elevation Myocardial Infarction (NSTEMI): -Loading dose: 300 mg orally once -Maintenance dose: 75 mg orally once a day -Duration of therapy: Optimal duration unknown. ST-Elevation Myocardial Infarction (STEMI): -Loading dose: 300 mg orally once (OPTIONAL) -Maintenance dose: 75 mg orally once a day, with or without thrombolytics -Duration of therapy: Optimal duration unknown. Comments: -Administer this drug in combination with aspirin 75 mg to 325 mg orally once a day. -The benefit of this drug for patients who undergo primary percutaneous coronary intervention is unknown. Uses: Prevention of atherothrombotic events in patients with non-ST-segment elevation acute coronary syndrome (UA, NSTEMI, those who are to be managed medically, those who are to be managed with coronary revascularization) and STEMI.

Usual Adult Dose for Ischemic Stroke:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Myocardial Infarction:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Peripheral Arterial Disease:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Detailed Adplatt dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Adplatt are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Adplatt if you are allergic to Adplatt components. Do not take Adplatt if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Adplatt if you suffer from or have a history of stroke, stomach ulcer or ulcerative colitis; liver or kidney disease, hemophilia. Be careful with Adplatt if you are taking such medicines as aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs such as naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ibuprofen (Motrin, Advil), (Toradol), ketoprofen (Orudis), nabumetone (Relafen), piroxicam (Feldene), ketorolac mefenamic acid (Ponstel), meloxicam (Mobic) and the others), phenytoin (such as Dilantin); torsemide (such as Demadex); medication used to prevent blood clots (alteplase (such as Activase), anistreplase (such as Eminase), dipyridamole (such as Persantine), streptokinase (such as Kabikinase, Streptase), ticlopidine (Ticlid) and urokinase (such as Abbokinase); fluvastatin (such as Lescol); a blood thinner (warfarin (such as Coumadin), heparin, ardeparin (such as Normiflo), dalteparin (such as Fragmin), danaparoid (such as Orgaran), enoxaparin (such as Lovenox), or tinzaparin (such as Innohep); tamoxifen (such as Nolvadex); tolbutamide (such as Orinase). It is not recommended to do sport while taking Adplatt because it can cause bleeding or bruising injury. If you are going to have a surgery you should stop taking Adplatt for 5 days before the surgery. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Adplatt suddenly.

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Modulation of cardiovascular effects produced by nitric oxide and ionotropic glutamate receptor interaction in the nucleus tractus solitarii of rats. Distributions and habitat associations of the bridled monocle bream Scolopsis bilineatus (Nemipteridae): a demographic approach. Detection of neuropsychological impairment among substance-abusing patients: accuracy of the neurobehavioral cognitive status examination. Careful anatomic studies of the blood supply to the abdominal wall and critical outcome analyses have resulted in many refinements in TRAM flap breast reconstruction. The phenotype ranges from a severe form similar to Patau syndrome, through to physical and mental normality. Chemistry manufacturing and controls, animal toxicology, and biopharmaceutical data are described. In addition, the contribution of the mini-invasive techniques and the computer-assisted surgery seem techniques with a promising future. Three layers were identified in the proximal arteries of 10 patients but could not be identified in the distal arteries of any patient.

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Revision osteochondral allograft transplantations: do they work?. Preoperative extracorporeal membrane oxygenation in newborns with total anomalous pulmonary venous connection. Using the Higgs boson as an example, we show that it may be found at the LHC on the first day of its operation, even with incomplete detectors. It appears that vitellogenin, the product of another estrogen-regulated gene in egg-laying species, is not synthesized by LMH-2A cells. Immunoglobulin-like folds have previously been identified in prokaryotic proteins but these share no recognizable sequence similarity with eukaryotic immunoglobulin superfamily (IgSF) folds, and may represent products of convergent evolution. This prospective, randomized, double-blinded study was designed to test the hypothesis that the intraoperative administration of remifentanil results in postoperative opioid tolerance in a dose-related manner in young children. Socio-demographic and medical characteristics of advanced cancer patients using conventional or complementary medicine.

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Older people constitute an increasingly greater proportion of patients with advanced CKD, including those patients undergoing maintenance dialysis treatment. Observations on the particular cutaneous and hepatic manifestations connected with the processing of tar. It could offer potential advantage in resection of rectal cancer as it has a lower conversion rates even in obese individuals, distal rectal tumours and patients who had preoperative chemoradiotherpy. Multiple studies in animal models have also shown that inhibition of MMP activity in animal models of heart failure have attenuated the onset of left ventricular dilatation. Clinical observations of dissociative states, and their comorbidity with symptoms of depression and psychotic illness, were confirmed empirically. We have dissected the minimal regions of vitronectin protein needed for effective integrin dependent cell adhesion and spreading. Despite the use of group-specific primers and efficient trapping systems with a bait plant consortium, surprisingly, two of the globally most frequently found species, Glomus intraradices and Glomus mosseae, were not detected neither as phylogenetic taxa in the date palm roots nor as spores under the date palms, the intermediate ruderal plant, or the surrounding natural vegetation. We demonstrate that the PHD1-PHD2 region is essential for viability and that the first PHD finger contributes to the preferred binding of PHD1-PHD2 to lysine 4-methylated histone H3 tails. Due to the role of inflammation in atherosclerosis, we aimed to determine the relationship between APO A2 -265T/C polymorphism and inflammation as a risk factor in type 2 diabetes mellitus (T2DM) patients.

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We propose that the specifics of gustatory responses grow not only out of information ascending from taste receptor cells, but also from the cycling of information around a massively interconnected system. Biochemical studies have addressed Chk2 structure, domain organization and regulation by phosphorylation. New prospective clinical trials may need to consider including sham arms to enhance their relevance. These were reflected in a marked increase in the proportion of cholic acid together with a decrease in that of deoxycholic acid, while the proportions of chenodeoxycholic acid and lithocholic acid changed only moderately. Gender equity and tobacco control: bringing masculinity into focus. We hypothesized that ITL-induced changes in cerebral activation may differ between single-breath ITL and continuous ITL, with differences resembling those observed after cortical automatization of motor tasks. Adult-born hippocampal neurons play important roles in certain forms of learning and memory, and altered hippocampal neurogenesis has been associated with a number of neuropsychiatric diseases such as major depression and epilepsy. This effect is probably unrelated to the reducing property of GSH since dithioerythritol (0.17-1.34 mM) does not mimic it. New imidazo(1,2-a)pyrazine derivatives with bronchodilatory and cyclic nucleotide phosphodiesterase inhibitory activities.

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Short access to 6-substituted pyrimidine derivatives by the S(RN)1 mechanism. We tested the hypothesis that slow naming speed is specific to RD. Inhibition of the formation of castration hypophysis by sodium phenyl-ethyl barbiturate. We used the introduction of syphilis rapid tests to illustrate the importance of programme science to address the gap between accruing evidence of acceptable test performance and the complexity of programme design, implementation and evaluation of test deployment to address public health needs and improve patient-important outcomes. Non-functioning malignant neuro-endocrine tumour of the pancreas: a case report with a review of the literature. The distance to the posterior nasopharyngeal wall was also shortened with age. The Italian Ministry of Universities, Research and Technology granted research funds totalling 50,000,000 Euros for the whole programme.

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FISH-deletion mapping defines a 270-kb short stature critical interval in the pseudoautosomal region PAR1 on human sex chromosomes. Another aim of the study was to determine whether temporal order discrimination is based on either familiarity or recollection-based memory processes. EGDT significantly reduced mortality in patients with severe sepsis and/or septic shock over 15 years since its publication. A method for fluorescence-optic demonstration of complement fixation and its use in the histo-immunological demonstration of experimental kidney anaphylaxis. Further, a decreased PON 1 activity may be a risk factor for CAD, which is likely to be explained by derangement of PON 1 activity towards lipid peroxidation. Some women in Tanzanian who suffer a perinatal loss in one pregnancy are at a particularly high risk of also losing the baby of a subsequent pregnancy. Widespread insults may alter the size, shape or colour of the nail plate. Plain radiographs were taken at 1 week, and 3, 6, and 24 months postoperatively, and tibial tunnel enlargement was evaluated.

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Piscine myocarditis virus (PMCV) in wild Atlantic salmon Salmo salar. We identified thousands of AR binding sites in CRPC tissue, most of which were not identified in PC cell lines. Selectivity of metal binding and metal-induced stability of Escherichia coli NikR. Patients were assessed objectively, during dynamic penile duplex ultrasound, as well as subjectively using a questionnaire before and after initiation of the treatment protocol. SlY1, the first active can you buy pepcid 20 mg over the counter gene cloned from a plant Y chromosome, encodes a WD-repeat protein. Comparison of spontaneous and evoked epileptiform activity in three in vitro epilepsy models. At 6 weeks after transplantation, the TS group showed a significantly smaller reduction in disc height than the IN group and exhibited a restoration of MRI signal intensity. The current study seeks to explain what might account for this relationship, using ANOVA models (Method) conducted on survey data from 3 cities.

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