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Alfarich (Calcitriol)

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Alfarich is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Alfarich is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Alfacal, Alfacip, Alphadol, Arachitol, Biocal, Calasto, Caldikind, Calgel, Calsure, Caltin, Caltop, Carcal, Cholical, Fovit, Laretol, Lctrol, Minroset, Osteobel, Ostriol, Primacal, Rical, Ritoca, Rolsical, Sorvate, Statbone, Vezocal, Vitalpha

Similar Products:
Detrol, Mysoline, Xanax, Eulexin, Abhigra, Zantac, Ancoril, Bezip, Mononaxy, Tricor, Danazol, Tiginor, Ethiflox, Loscard, Sanprazole, Clinimycin,

Also known as: Calcitriol


Generic Alfarich is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Alfarich are intestine and bone. Generic Alfarich receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Alfarich may also act on the kidney and the parathyroid glands. Generic Alfarich is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Alfarich has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Alfarich, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Alfarich in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Alfarich produces other independent beneficial effects. Alfarich is also known as Calcitriol. Generic Alfarich treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Alfarich is Calcitriol. Brand name of Generic Alfarich is Alfarich.


This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Alfarich. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.


If you overdose Generic Alfarich and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfarich are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


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A 13-year-old patient had rectal cancer and underwent curative surgery. Primary outcomes were early (in ICU or within 30 d) and late (in hospital or after 30 d) mortality. Modes of occurrence of accidental ingestions in children and a suicide attempt. We present a characterization of bos5 from Botrytis cinerea, a gene that encodes a mitogen-activated protein kinase kinase (MAPKK), which is homologous to OS-5 of Neurospora crassa. As with cetuximab, it is most likely that these new agents will first find a niche in the context of combination regimens with standard anticancer therapeutics. Percutaneous intentional extraluminal recanalization in patients with chronic critical limb ischemia.

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Metaproteomic data analysis at a glance: advances in computational microbial community proteomics. Analysis of the DMN showed statistically significant increased activation in the posterior cingulate cortex (PCC) and left inferior parietal lobule (lIPL). Based upon the use of LearnCoil-VMF, as well as other computational tools, we report detailed sequence analyses of coiled-coil-like regions in retrovirus, paramyxovirus and filovirus membrane-fusion proteins. Our results therefore contradict a previous report (Zhou, J., Fernandez-Velasco, J. Surgical treatment of malignant fibrous histiocytoma in the left atrium and pulmonary veins: report of a case. Trypanosoma evansi: identification and characterization of a variant surface glycoprotein lacking cysteine residues in its C-terminal domain. A stereoselective intramolecular 1,3-dipolar nitrone cycloaddition for the synthesis of substituted chromanes. We have concentrated on the adenovirus as the source of the heightened inflammatory response of the lungs of patients with COPD. It is roughly estimated that over 100 million tonnes of CO(2) have been unintentionally sequestered in red mud around the world to date through the natural weathering of historically produced red mud.

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Lymphangiomas are rare benign tumors that are congenital malformations of the lymphatic system. At the present we dont know clearly the differences in cutaneous reactivity among several house dust mites species. Old mice express a transient early resistance to pulmonary tuberculosis that is mediated by CD8 T cells. Progress in defining this large and complex system has been dependent on the research technologies available, but since the introduction of protein chromatography, electrophoresis, and antibody-based assay methods in the 1950s and 60s, and sequencing of proteins and DNA in the 70s and 80s, there has been very rapid accumulation of data. Unfortunately, in the majority of patients neuroblastoma is metastatic at the time of diagnosis, and it usually undergoes rapid progression with a fatal outcome. Arguments have been made that the culture of nursing homes (NHs) must change to improve the quality of care, and two initiatives have been designed to accomplish this goal. While the circular ssDNA virus represents the third to be detected in association with a marine invertebrate, transmission trials are needed to confirm its infectivity for F. Harmonic forcing of an extended oscillatory system: homogeneous and periodic solutions. The International Registry of Lung Metastases (IRLM) staging system, resection status and surgical approach were documented.

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The total toxicological screening and the quantitation of both the ingested drugs and its inactive isomer (E)-trans-clopenthixol (E-CPT, produced by in vivo isomerization) in postmortem fluids and viscerae were produced by high-performance liquid chromatography (HPLC)-diode array detection. Furthermore, the GSH level was decreased in the infarcted cortex. The performance of some kinetic energy density (tau) dependent functionals in predicting the effective Heisenberg exchange has been explored using the KNiF3 and K2NiF4 insulators as case examples. The etiology and risk factors for ischemic stroke in children and adolescence differ from those typical in adults. Despite the potential advantages of using reputation to promote positive behaviors, there are several risks and limits. Bacteria were treated with Al(III) at 37 degrees C and 4 degrees C, then exposed to free radicals or nisin. An analysis of DNA content (ploidy), cellular proliferation, and p53 expression. The structures and relative configurations of 1-7 were determined through spectroscopic observations, and the absolute configurations were defined by CD analysis. The vestibular flap technique was used for half the implant fixtures and the crestal incision for the other half. A laparoscopic approach was used for penile revascularization in a patient with vasculogenic impotence to avoid the long abdominal incision which was traditionally required to harvest the inferior epigastric artery as a neoarterial source.

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However, extracellular ATP alone seems not to be sufficient to elicit the enhanced synergistic effect on cytokine and chemokine expression observed by pre-stimulation of primary human macrophages or THP-1 cells with HBD2 or HBD3. Three types of retreats held for veterans, service members and their families, as well as professional service providers, were evaluated. An orientational relationship between the hexagonal and the parent cubic phase was also observed. As the CD14 gene promoter polymorphism -159C/T and some bacterial infections may affect the sCD14 levels, we compared the impact of both the CD14 promoter polymorphism and Helicobacter pylori infection on serum sCD14 levels in 201 dyspeptic patients (group 1) who had undergone gastroscopy, and 127 staff members (group 2) with no endoscopy. Assessment of 12-month safety of ospemifene 60 mg/day for treatment of postmenopausal women with vulvar and vaginal atrophy (VVA). This study assessed the in vitro activity of dapsone versus Gram-positive and Gram-negative bacterial pathogens obtained from patients with infections. By understanding the basic principles of PN and recognizing the potential toxicities of specific chemotherapy drugs, nurses can take an active role in minimizing their occurrence. EGCG differs from insulin, however, in that it affects several insulin-activated kinases with slower kinetics. Women who participated in the group intervention programs did not differ from women in the control group regarding psychosocial adjustment at the end of the study. In this review, we focus on the pressure-driven confined flow behavior of isolated droplets in circular and rectangular cross-section channels, which are valuable model geometries to gain insight into more complex flow conditions found in industrial applications.

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The explosion of new information on neurotrophins, however, has revealed that neurotrophin 3 (NT3) is critically involved in several aspects of this development, including the initial differentiation, survival, and perhaps even the terminal arborizations of muscle sensory neurons within the spinal cord. Current studies suggest that post-TBI emergent psychopathology, including OCD, is influenced by underlying sub-clinical diathesis, brain injury lesions sites, environmental stressors and the rehabilitation process. In the last decades the prevalence of allergic diseases and eczema raised significantly, and today they are the most common chronic pathologies affecting children. Even for normal incidence, the angular dependence of the re-radiated wavefront disturbs the overall performance of the reflectarray. Phase 1 involved screening of all individuals aged 60 and above with the help of a cognitive screen specifically developed for the tribal population. Lack of MHC expression and retention of ultrastructural characteristics by xenograft transmissible venereal tumor cells in SCID mice. Comparison of the efficacy of a subunit and a live streptomycin-dependent porcine pleuropneumonia vaccine.

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Future strategies that have indirect support but have not yet been tested in clinical studies include anticytokine therapy and ischemic preconditioning. Tuberculous peritonitis: a review of 34 cases with emphasis on the diagnostic aspects. Moreover, the cellular compartments in which these foci are concentrated depend on the transposase, and on its expression. Bivariable analyses demonstrated an association between female sex, the presence of dyspnea, the need for oxygen, past steroid use, and the use of corticosteroids immediately prior to diagnosis with the use of corticosteroids at the time of diagnosis. Serum retinol levels, anaemia, pregnancy-induced hypertension, birthweight and gestational age of the infant. As the traditional risk factors for oral squamous cell carcinoma, especially tobacco, decline, new potential causative agents become the focus of research. Endothelin-1, an important mitogen of smooth muscle cells of spontaneously hypertensive rats. We herein report a rare case of cutaneous metastasis of pulmonary sarcomatoid carcinoma that contains liposarcomatous, rhabdosarcomatous and chondrosarcomatous heterologous differentiation, and review relevant literatures to lead to a better understanding of this rare but highly aggressive tumor. prionitis were statistically equally effective against dental plaque.

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To evaluate changes in referral times and patient awareness among men with testicular cancer in Yorkshire over the past 18 years. To assess the amniotic fluid levels of these antibiotics, 10 pregnant women were given moxifloxacin, 10 were given levofloxacin and 6 were given cefixime orally 2 h before amniocentesis as a single dose for prophylaxis. Cox proportional hazards regression was used to determine whether tritium was associated with radiation-sensitive cancers in Pickering. Expression of CDM2 was shown to be transcriptionally upregulated in the primary CEF cells where p53 was activated by either mitomycin C treatment or by the exogenous transfection of the chicken p53 cDNA. Illumination in lux was averaged for 4 hours before bedtime and over 24 hours. Physical inactivity is the major determinant of obesity in black women in the North West Province, South Africa: the THUSA study. Screening and intervention for intimate partner abuse: practices and attitudes of primary care physicians. We found a 2- to 10-fold higher uptake of LDL in five out of five drug resistant K562 cell lines. Reliability of the Health Enhancement Lifestyle Profile-Screener (HELP-Screener). Phase I study of (131)I-anti-CD45 antibody plus cyclophosphamide and total body irradiation for advanced acute leukemia and myelodysplastic syndrome.


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Morphological and histochemical studies on kollidon excretion through the kidneys. Temporary threshold shifts at 1500 and 2000 Hz induced by loud voice signals communicated through earphones in the pinball industry. Problems are mostly in the area of self-care, with equipment provision the most frequent intervention provided. A comparison of the effect of early insertion of standard latex and silver-impregnated latex foley catheters on urinary tract infections in burn patients. Left prefrontal rTMS (with the used parameters) seems to produce a significant nonspecific effect of the treatment procedure but no therapeutic effect in the most chronic and severely ill schizophrenia patients. This resistance to drug-induced apoptosis is likely to play an important role in tumors that are refractory to chemotherapy. In experiments to elucidate its mechanism of action, xanthohumol was found to suppress RANKL-induced expression of TRAF6, GAB2, ERK, c-Src, PI3K, and Akt genes. A cultural change within the profession, allowing more time for reading and discussing research reports should be encouraged. Intracellular localization of polyoma virus antigen demonstrated with fluorescein-labeled antiserums.

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Prostate cancer is the most common cancer in elderly men in Western countries. Ultrasound may provide information about variations of PG content via speed of sound measurement. Multidrug resistance and anticonvulsants: new studies with some enaminones. We therefore examined the relationships between the intensity of root foraging and plant body traits across species in order to estimate the degree of coordination between plant body traits and root foraging as a form of plant behavior. However, no difference was observed when the activity was normalized to the amount of biofilm, despite decreasing proportions of AOB how long after drinking alcohol can you take ambien to all bacteria with depth in the NTF. The EMG frequency content suggests two different contraction mechanisms or a different origin of the EMG in the cervix.

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This resulted in a theoretically clinically significant difference of two segments. C-reactive protein (CRP), an obesity-related inflammatory marker, is a promising predictor for cardiovascular disease and may be a mediator for atherogenesis. Early decline in lung function after normal growth is associated with a genetic polymorphism that may also protect against early decline in reduced growth groups. As with others in this subgroup, the cytosolic domain of Siglec-11 is phosphorylated at tyrosine residue(s) upon pervanadate treatment of cells and then recruits the protein-tyrosine phosphatases SHP-1 and SHP-2. In rabbits the newly synthesized conjugate vaccines elicited high-titered, type-specific antibody that was opsonically active in vitro. In the past some scepticism existed among gastroenterologists who quoted the poor surgical results they had seen. In planar bilayers and in erythrocyte membranes, the proteolytically nicked toxin actually formed channels with a slightly smaller diameter (approximately 1.2 times) than that formed by the native toxin. The bone segment was subjected to a vertical load, and the load-displacement curves, wire tensions and wire tensile stresses were obtained under a full cycle of loading and unloading regime. This solution has been withdrawn from the belgian market probably because of the toxic effects related to the presence of polyoxyl 35 castor oil.

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This study evaluated clinical criteria as well as unilateral directed versus bilateral BAL for VAP diagnosis. Periodontal disease is one of the most prevalent dental diseases which affects the adult population of do you have to be 18 to buy zyrtec the world, varying only in degree from mild to severe. In this paper, six possible reconstruction algorithms that allow image reconstruction from projections with a finite range of scattering angles are investigated. Retention of study participants in randomized controlled trials (RCTs) is crucial to study validity. All tumors except one were immunopositive for one or more gonadotropins. After removal of the tumor, the flap was used to cover the intraoral defect. Here, we screened a monoclonal mouse antibody against gC1qR to prevent cell migration by neutralizing cell-surface gC1qR. Although factor VIII (FVIII) and von Willebrand factor (VWF) are products of two distinct genes, they circulate in plasma as a tight non-covalent complex. In this study, we evaluated subcutaneous (sc) morphine in combination with multimodal analgesia for postoperative pain control after radical nephrectomy and pyeloplasty with flank incision.

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Cytokine mRNA expression was analysed by RT-PCR in fresh peripheral blood mononuclear cells (PBMC) from normal individuals and in populations of activated T lymphocytes, derived from phytohaemagglutinin (PHA)-stimulated PBMC. Gene expression profiling of NB4 cells following knockdown of nucleostemin using DNA microarrays. Sensitivity in vitro of Plasmodium falciparum to three currently used antimalarial drugs on the western border of Thailand. The evidence strongly suggests that two variants (C1787S in BRCA1 and D2723H in BRCA2) are deleterious, three (R841W in BRCA1 and Y42C and P655R in BRCA2) are neutral, and one (R1699Q in BRCA1) remains of uncertain significance. Sunscreens with high SPF values are not equivalent in protection from UVA induced polymorphous light eruption. This article highlights concepts in pharyngoesophageal reconstruction emphasizing a thought process used when choosing cefpodoxime 200 mg bid reconstruction options based on the anatomical defect. Imbalance in expression of these factors is associated with malignancy in several cancers. Antenatal exposure to atenolol and retroperitoneal fibromatosis. By 40 days post-injection, the specific LacZ expression was restricted to the most immature germ cells in the basal portion of the seminiferous tubules.

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A prompt diagnosis of this complication and elimination of the underlying cause led to the return of somatosensory evoked potential waveforms, and there was no relevant neurologic deficit at the end of the surgery. After 2.8 (2.5 to 3.0) years all the surviving patients described symmetric functional conditions. In this study, colocalization of PTP with (Met)enkephalin in regulated secretory vesicles was assessed by immunochemical approaches. Lactobacillus helveticus Lafti L10 supplementation reduces respiratory infection duration in a cohort of elite athletes: a randomized, double-blind, placebo-controlled trial. The goodness of fit for the factor structure of the Community Integration Questionnaire, separating items into Home Competency, Social Integration, and Productive Activity, was satisfactory for whites but not for blacks or Hispanics. Novel echocardiographic parameters of aortic insufficiency in continuous-flow left ventricular assist devices and clinical outcome. Metabolic genotypes of 5,10-methylenetetrahydrofolate reductase (MTHFR) and folate status on oxidative DNA lesions in hepatocellular carcinoma (HCC) has not been elucidated. Under high DEZn flow rate, the ZnO nanowall-network structures were found to grow vertically on the sapphire substrate without using any metal catalysts. This time-scale separation allows to treat the hopping dynamics as a hierarchical process, RG step being a transformation between the levels of the hierarchy. These collateral pathways include intrahepatic interlobar collateral vessels, right gastric to left gastric arterial anastomoses, left hepatic to left gastric arterial anastomoses, and peribiliary arterial plexuses.

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