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Alfatrim (Trimethoprim)

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Alfatrim (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

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Also known as: Trimethoprim


Alfatrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Alfatrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Alfatrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


Take Alfatrim exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Drink plenty of fluids to prevent kidney stones while you are using this medicine.

Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Alfatrim.

Store at room temperature away from moisture, heat, and light.

Detailed Alfatrim dosage information


If you overdose Generic Alfatrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alfatrim overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Alfatrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Alfatrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Alfatrim is contraindicated in pediatric patients less than 2 months of age. Alfatrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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