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Allerzine (Cetirizine)

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Allerzine is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body. This medicine is generally very safe. The most common side effects include feeling sleepy or dizzy.

Other names for this medication:
Affycet, Alergo, Alrin, Ariwa, Atcet, Bocet, Cecold, Certiwon, Cetariv, Cetchem, Cetcold, Cetconil, Cetnac, Cetrish, Cetriwal, Cetzid, Cetzin, Cetzine, Cezor, Cinzim, Cistin, Citol, Citrazan, Corycet, Enecet, Histanit, Incold, Lexicet, Metacold, Metriz, Nimucet, Onacold, Oncet, Raucold, Relent, Relif, Sarcold, Silpazine, Simozine, Sinocet, Smicet, Starzine, Synomine, Terbolax, Turant, Zimat, Zirtin, Zucet

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Also known as: Cetirizine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


Usual Adult Dose for Allergic Rhinitis:

5 to 10 mg orally once a day -Maximum dose: 10 mg/day -Some experts recommend: Patients over 65 years of age should start with 5 mg orally once a day.

Usual Adult Dose for Urticaria:

5 to 10 mg orally once a day -Maximum dose: 10 mg/day -Some experts recommend: Patients over 65 years of age should start with 5 mg orally once a day. Uses: -Relief of symptoms associated with perennial allergic rhinitis due to allergens (e.g., sneezing, rhinorrhea, postnasal discharge, nasal pruritus, ocular pruritus, tearing) -Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria

Usual Pediatric Dose for Allergic Rhinitis:

6 months to 2 years: -Initial dose: 2.5 mg orally once a day -Maintenance dose: 2.5 mg orally once to 2 times a day -Maximum dose: 5 mg/day 2 to 5 years: -Initial dose: 2.5 mg orally once a day -Maintenance dose: 2.5 mg orally 2 times a day OR 5 mg orally once a day -Maximum dose: 5 mg/day 6 years and older: 5 to 10 mg orally once a day -Maximum dose: 10 mg/day

Usual Pediatric Dose for Urticaria:

6 months to 2 years: -Initial dose: 2.5 mg orally once a day -Maintenance dose: 2.5 mg orally once to 2 times a day -Maximum dose: 5 mg/day 2 to 5 years: -Initial dose: 2.5 mg orally once a day -Maintenance dose: 2.5 mg orally 2 times a day OR 5 mg orally once a day -Maximum dose: 5 mg/day 6 years and older: 5 to 10 mg orally once a day -Maximum dose: 10 mg/day Uses: -Relief of symptoms associated with perennial allergic rhinitis due to allergens (e.g., sneezing, rhinorrhea, postnasal discharge, nasal pruritus, ocular pruritus, tearing) in patients 2 years and older -Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria in patients 6 months and older

Detailed Allerzine dosage information


If you overdose Allerzine and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Allerzine overdosage: extreme sleepiness, confused mental state, weakness.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Side effects

The most common side effects associated with Allerzine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to cetirizine or pseudoephedrine, or if you have:

narrow-angle glaucoma; severe high blood pressure (hypertension); severe coronary artery disease; if you are unable to urinate; or if you are allergic to hydroxyzine (Atarax, Vistaril).

Do not use Allerzine-D if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

heart disease, coronary artery disease, high blood pressure, or heart rhythm disorder; diabetes; a thyroid disorder; glaucoma; kidney or liver disease; an enlarged prostate; or problems with urination.

FDA pregnancy category C. It is not known whether Allerzine-D will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Cetirizine and pseudoephedrine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Older adults may be more likely to have side effects from Allerzine-D.

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The canine prostate is a widely used and well established animal model for the assessment of therapeutic effects of laser technology in the search for better options for the treatment of benign prostatic hyperplasia. Histamine clearly provoked erythema and swelling at the prick site, whereas the mast cell-degranulating compound 48/80 even more pronounced caused wheal and flare reactions known from the human prick response. The role of shuttling in lytic DNA replication and virus growth is unknown. We found that neighbor contrast defense and associational susceptibility can both be explained by simple foraging rules of energy maximization. Formalin-fixed and paraffin-embedded (FFPE) tissue samples of 234 gliomas were collected including the matched blood samples in 30 patients. Metabolic consequences of localized application of electrical pulses to sections of cerebral white matter. These data indicate that community monitoring studies should use multiple sampling methodologies to avoid bias. Here we describe the clinical features and histological parameters of 1 case of IP. Statistical analysis was performed by Student t test and chi(2) test. The proximate analysis showed that protein, ash and fiber values were comparable to Parkia africana seeds.

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This article describes the evidence about why reading aloud to children is important to help them develop the language and early reading skills necessary for school readiness. We conducted a prospective randomized trial comparing stapled with nonstapled laparoscopic TAPP inguinal hernia repairs in a series of 502 consecutive patients undergoing elective inguinal hernia repair at two institutions between January 1995 and March 1997. Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells. Solo emergency care by a physician assistant versus an ambulance nurse: a cross-sectional document study. These results suggest that phasic alertness may modulate visual processing and consequently, affect global/holistic perception. Anti-centromere antibody is an independent risk factor for chronic kidney disease in patients with primary biliary cirrhosis.

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At the same time the dose cleocin antibiotic family of 1.5 binding units (BU) of PST, inhibiting spontaneous proliferation in vitro, induced strong proliferative response in combination with the suboptimal dose of Con A (1 microgram/ml). The number of outpatient surgeries has dramatically increased in the last several years, particularly in the orthopaedic sector. High-density lipoprotein metabolism in familial hypercholesterolaemia: significance, mechanisms, therapy. Race/ethnic disparities in left ventricular diastolic function in a triethnic community cohort. We therefore hypothesized that A-T is due to oxidative damage resulting from loss of function of the A-T gene product. The stoichiometry of PDE6-PrBP/delta binding and the mechanism by which the PDE6-PrBP/delta complex assembles have not been fully characterized, and the location of regulatory PDE6gamma subunits within the protein assembly has not been elucidated. Compared with placebo, Z drugs produce slight improvements in subjective and polysomnographic sleep latency, especially with larger doses and regardless of type of drug.

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