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Alpkair (Alprazolam)

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Alpkair is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpkair is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpkair may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alltop, Almac, Alparazole, Alpkair, Alprasan, Alprazolam, Alprine, Alpronit, Alzac, Alzoft, Alzorix, Ambulax, Ambusyn, Anlzium, Anzilum, Apsolam, Aryalam, Ateez, Axnil, Berest, Cardilax, Depsolam, Dexolam, Erazol, Hiprazole, Jolistar, Mediprex, Mentolift, Notence, Prolam, Prozam, Restyl, Samprex, Sertakem, Sinaday, Sinzolam, Sowel, Synozolam, Tenan, Trazopin, Visram, Zamitol, Zedel, Zodia, Zolent, Zolyde, Zopain

Similar Products:
Calan, Imodium, Tenormin, Rulide, Symmetrel, Flonase, Xalatan, Antabuse, Premelle, Clarocin, Proscar, Nugrel, Itracross,

Also known as: Alprazolam


Alpkair XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alpkair XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alpkair XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpkair. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alpkair for medical reasons, the best way to avoid a Alpkair overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpkair consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpkair dosage information

Side effects

The most common side effects associated with Alpkair are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3. This identifies aortic punches collected during CABG as another biomarker source related with atherosclerosis severity and possible clinical outcome. Autoimmunity and malignancy co-exist frequently, and share etiological and pathological mechanisms. There were 111 cases of newly diagnosed hepatocellular carcinoma during 92,359 person-years of follow-up. Treatment of various OSCC cells with MPT0B098 induced growth inhibition, cell cycle arrest and apoptosis, as well as increased the protein level of SOCS3.

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Cloning, characterization, and expression analysis of goat (Capra hircus) phospholipid hydroperoxide glutathione peroxidase (PHGPx). Local administration precludes systemic adverse effects even though the risk of developing cataract or glaucoma remains an important issue. Measurement of perfusion and permeability from dynamic contrast-enhanced MRI in normal and pathological vertebral bone marrow. Programs used in this work and numerical results are available upon request. Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network. Our restrictive criteria identified 323,415 hospital admissions in 3 years relating to diseases eligible for pediatric palliative care, which involved approximately 12,000 children. Wounds were irradiated by a He-Ne laser (632.8 nm, 1.5 J/cm2) on the 2nd, 3rd, and 4th days after the beginning of the experiment. The influence of the drying process (tray- or freeze-drying), the granulation liquid viscosity, and the drying time during tray-drying on the inter- and intragranular migration of both a water-soluble and a poorly water-soluble compound in a granulation mass and in a compact were quantitatively assessed.

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Variation in the shape and dimensions of the acrosomal vesicle and nucleus is substantial in these four Veneroidea species. There was no difference in the expression of intracellular IFN-y, or IL-4 between SLE patients and healthy controls. Distributions of PHB-degrading microorganisms, factors affecting the biodegradability of PHB, and microbial and enzymatic degradation of PHB are discussed in this review. For repulsive systems, the theory somewhat overpredicts the density oscillations near a surface. The advanced decay and dry remains stages were dominated by high relative amounts of phenol.

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Etiology and significance of hypoglycemia in pneumococcal septicemia. The coexistence of CN and SCN phenotypes in this kindred with a shared paternal haplotype strongly suggests both a role for modifying genes in determination of congenital neutropenia disease phenotypes, and the classification of CN and SCN within a spectrum of phenotypes expressing varying degrees of the same disease process. A longer duration of homelessness is associated with poorer health outcomes. Methylmercury induces neurite degeneration in primary culture of mouse dopaminergic mesencephalic cells. Additionally, it may be advisable to perform gonioscopic examinations to look for any abnormal accumulation of material in the angle. The aim of this study was to develop a more suitable method to estimate BEE in Japanese patients with diabetes using indices readily measured in clinical practice. Nitric oxide and nitric oxide synthases in the fetal cerebral cortex of rats following transient uteroplacental ischemia. Efficient cellular accumulation of nanogels and the consequent increase in intracellular levels of NATP were found to be the major factors determining cytotoxic efficacy of nanoformulations. We conclude that disparity of temporal scales between migration and local dynamics may have important consequences for the maintenance of biodiversity in spatially structured populations.

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This review discusses the synthesis, structure-activity relationships and therapeutic potential of A(1)AR agonists. Further investigation of the effect of tubocurarine on the transport of particles by cilia of the frog oesophagus has confirmed that, when Ringer solution buffered with bicarbonate was used, tubocurarine inhibited the movement in a concentration of 10(-6) g./ml. Enactments are a potential common clinical process factor contributing to positive outcomes in many relational therapies. Triptolide, the major component of the diterpenoids of the Chinese herb Tripterygium wilfordii Hook f. Simultaneous bilateral lobar lung transplantation derived from one large donor into two small recipients is reported.

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Theory of intrinsic linewidth based on fluctuation-dissipation balance for thermal photons in THz quantum-cascade lasers. Furthermore, the associations of serum 25(OH)D with mortality, particularly due to cardiovascular disease (CVD) and colorectal cancer, were modified by magnesium intake, and the inverse associations were primarily present among those with magnesium intake above the median. It provides accurate description of the fistula within the anal canal in relation to the sphincter complex and other pelvic floor structures as well as the associated complications such as abscess. Government agencies and national organizations recommend that physicians counsel their child and adolescent patients about preventive health topics. Our objective was to compare the functional characteristics and tissue effects of four energy-based surgical dissection and coagulation modalities on the rabbit liver. A physiologic discussion of the vascular reactions following pulmonary arterial obstruction by emboli of varying size. Intratracheal administration of a nuclease inhibitor (ATA) with naked DNA (0.5 microg ATA/g body weight) enhanced direct transfection efficacy in macaque lung by over 86-fold and by over 54-fold in mouse lung. One of the major immune checkpoints responsible for immune evasion in cancer cells is the interaction between programmed cell death-1 (PD-1) and its ligand (PD-L1).


Based on a recent episode involving priority determination between two competing names of the same fungal plant pathogen, this letter wishes to open a discussion on the ethics of scientific publications and points out the necessity of a correct management of the information provided through personal communications, whose traceability would prevent their fraudulent or accidental manipulation. These findings provide support for the use of sex-specific sonographic models for fetal weight estimation as well as the use of sex-specific reference growth charts. This study describes health-related quality of life (HRQL) in a large sample of molecularly defined familial hypercholesterolemia (FH) patients compared with unaffected relatives. Morphology of inhibited larvae of the bovine lungworm Dictyocaulus viviparus. pastoris (iPP668), composed of 1,361 reactions and 1,177 metabolites, was reconstructed based on its genome annotation and biochemical information. Excessive prolongation of the Ivy bleeding time after aspirin in essential thrombocythemia is also demonstrable in vitro in the high shear stress system PFA-100. The EQ-5D index values were calculated based on the Chinese Time Trade-Off values set. Cells were stained with anti-CD4 fluorescein isothiocyanate-conjugated monoclonal antibody, and then anti-human IL-4 phycoerythrin, IL-5, or IL-13 monoclonal antibody, respectively, was added to both blocked and stained samples. Osteoplastic laminotomy as a minimally invasive spinal procedure.

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Late urological complications and malignancies after curative radiotherapy for gynecological carcinomas: a retrospective analysis of 10,709 patients. A focused panel of 84 genes involved in cell cycle progression was also examined. Effective self-management and adherence to inhaled corticosteroids are issues of particular interest in comprehensive asthma care. Cardioprotective effect of enalapril in renovascular and angiotensin II hypertension. For porosity, four samples from each sealer were prepared and scanned using a SkyScan 1072 Micro-CT. Many of these disease states share a tissue failure phenotype, such as loss of bone marrow cells or failure of pulmonary epithelium, suggesting that stem cell dysfunction is a common pathophysiological mechanism underlying these telomere diseases.

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In the present study, we examined whether these clones cross-reacted with Japanese encephalitis virus (JEV), which belongs to the same virus family. Obtaining structural information on these nucleoprotein complexes has been a major bottleneck in fully understanding the mechanism of action of telomeric nucleoproteins for over two decades. This study compares the influence of long-term and short-term depletion and loading of hepatocytes with iron on the uptake of non-transferrin bound iron, its affinity, specificity and the interaction with the transferrin-mediated pathways. Selective posterior rhizotomy and intrathecal baclofen for the treatment of spasticity. It is concluded that without additional resources enhanced key-worker liaison for psychiatry in primary and secondary care has limited benefits although this does not necessarily apply to other forms of liaison practice.

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It gives visually sparse pictures of large volumes which are useful for initial fitting and for molecular-boundary determination. The outbreak occurred in nine herds, and 358 animals that shared grazing lands during the summer season were affected. PS, also expressed on apoptotic cells (ACs) enables macrophages to phagocytose ACs. Determination of catecholamines and metanephrines in urine by capillary electrophoresis-electrospray ionization-time-of-flight mass spectrometry. The higher values could result from higher losses of (15)N depleted gases or lower losses of enriched (15)N material. Here, we summarize and discuss current concepts and controversies in the field of innate immunity in CF lung disease, facing the ongoing questions of whether inflammation is good or bad in CF and how innate immune mechanisms could be harnessed therapeutically. Patients should be encouraged to exercise caution and to utilize only well-known sites and those that display the HONcode seal of compliance with transparency and accountability practices.

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We were able to show that the integration and inference components were related to narrative comprehension processes, but the coordination of alternative models was not. A patient suffered massive bleeding from the ruptured liver and laceration of the inferior vena cava due to traffic accident, and developed hypotension and decreased level of consciousness. Although BCKDHK has been shown to have serine autophosphorylation activity, we speculate, based on the results from this study and other supporting evidence, that BCKDHK may also have intrinsic histidine kinase activity. These processes are ultimately controlled by the cell nucleus, because the requisite proteins are all encoded by nuclear genes and imported into the mitochondrion. Comparison of the monitored versus nonmonitored presentation of stimuli demonstrated significant activity in a rostral/dorsal division of the right ACC, anterior to SMA. In that case the distribution of the number of infected individuals per household reaches a stationary distribution described by a birth-death process with a constant immigration term. CHO cells were exposed to thermal neutrons and their mutation frequency was determined.

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High intake of linoleic acid in a diet deficient in other polyunsaturated fatty acids and in riboflavin results in high tissue production of prostaglandin E2, which in turn causes inhibition of the proliferation and cytokine production of Th1 cells, mediators of cellular immunity. The aim of this study was to assess the protective effect of hulls covering the spelt kernels on Alternaria toxins. The rabbits were euthanatized at different times after transplantation, and the retinas were studied histologically. These data suggest that brain-emigrant DCs are sufficient to support activated T cells to home to the tissue of DC origination. Current therapeutic methods and indications in malignant tumorous disorders of the blood and of the hematopoietic organs. Almost 3,000 calls were taken by three psychiatric nurses working at the Mental Health Information Centre.

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A commercially available wireless passive marker system that allows the calibration and tracking of virtually any instrument was adapted to children and used during pediatric endoscopic sinusonasal surgery. This debate has been fueled by indications that many trauma-exposed individuals evidence partial presentations of PTSD that are associated with significant impairment and help-seeking behavior. Previous reports regarding the effect of cAMP on keratinocyte proliferation are contradictory and indicate that the effect apparently depends on cellular density. Previously, we reported that LIF inhibits, in a non-IL-6-dependent manner, osteoblast differentiation and bone nodule formation in the rat calvaria (RC) model, an effect that is antagonized by dexamethasone (Dex). Spontaneous conversion of atrial fibrillation to normal sinus ultram dose rhythm following recurrent cerebral infarctions. Some of these are, or have been, in clinical trials for rheumatoid arthritis, pain, and cough. Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects. To avoid the detection of effects related to secondary and tertiary inflammatory messages, we compared gene expression in sarcoidosis with that of tuberculosis and extrinsic allergic alveolitis. A synthetic peptide library comprising 377 in vivo phosphorylation sequences from developing seed was screened using 71 recombinant A. Therefore, in addition to the antagonistic action of these agents on the alpha-1 adrenergic receptors of prostatic smooth muscle, both agents (especially naftopidil) may also act on the lumbosacral cord, and thus may improve collecting disorders in patients with benign prostatic hyperplasia.

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That spatial distribution of quantum fluctuations is functionally the same as that appearing in the Feynman-Kleinert variational local harmonic approximation, and also that implemented in existing classical trajectory-based estimates of coherence dissipation times. Use of secondary preventive drugs in patients with acute coronary syndromes treated medically or with coronary angioplasty: results from the nationwide French PREVENIR survey. Protective factors, such as potentially, and breastfeeding, are few and very important. Detection of an anatoxin-a(s)-like anticholinesterase in natural blooms and cultures of cyanobacteria/blue-green algae from Danish lakes and in the stomach contents of poisoned birds. and more rarely Gasterosteus aculeatus, Oncorhynchus mykiss and O.

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This result suggests that a major mutagen in chlorinated fenitrothion will be produced via a chemical reaction between chlorine and 3-methyl-4-nitrophenol. The subjects consumed a low HCA-containing diet for 1 week followed by a high HCA diet for the subsequent week. The activity of the conditioned medium was not diminished, but enhanced by heat treatment, which was consistent with the unique property of TGF-beta family of molecules. After three months, the creation of a temporary inferior nasoantral window did not change the maxillary sinus mucosa and did not increase the rate of sinus infections in rabbits. Multiple mechanisms have been noroxin drug class advocated to explain the relationship between H.

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Effect of human bone marrow mesenchymal stem cell transplantation on hematopoietic recovery of irradiated mice. Autophagy pathway might be involved in the production of pro-inflammatory cytokines and cytotoxic factors in microglia, though details of the mechanism remain largely unknown. By contrast, the proximally located vesicle pool was much less intensely stained. Suppression of survivin expression with small interfering RNA rendered human lung epithelial cells susceptible to bleomycin-induced damage, with markedly upregulated activation of caspase-3, caspase-7, poly (ADP-ribose) polymerase, and lactate dehydrogenase activity and an increased number of dead cells compared with mock small interfering RNA-treated cells. Subchondral insufficiency fractures of the femoral head (SIF) need to be differentiated from osteonecrosis of the femoral head (ON), since these two conditions have several overlapping characteristics especially in their radiological findings.

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The significance of this conductance to the functioning of the electrically active neuron, and to higher cognitive function is also discussed. Where changes in gene expression profile are concerned, exposure to PCB 126 showed the greatest effects. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on the release of progesterone by trophoblast cells in vitro. NOC-18 and L-arginine reduced the migration of inflammatory cells and edema, lowered oxidative stress, and normalized antioxidant enzyme activities. These psychological processes can be solicited to reduce clinical pain and we speculate that they may further attenuate or promote central mechanisms involved in the transition from acute to persistent pain states. Underlying cultural factors might explain the unsatisfactory reliability of the general health domain. MMF can be used in the case of intolerance to cyclophosphamide and might be the first choice in black and Hispanic patients. Computational methodologies applied to X-ray powder diffraction (XRPD) data from these systems are also shown to reliably detect the presence of phase separation.

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Here we show that a decreased expression of reelin mRNA by hippocampal Cajal-Retzius cells correlates with the extent of migration defects in the dentate gyrus of patients with temporal lobe epilepsy. To test this application of lacZ intracistronic complementation, proteins that form a complex in the presence of rapamycin were used. Expression of SLAM as a functional and phenotypic marker in women with recurrent miscarriage. Pursuing magnet designation: choosing a professional practice model. Zero-dimensional noise is not suitable for characterizing processing properties of detection mechanisms. The physiological significance of positive and negative ionization of the atmosphere. Recent evidence suggests that this complex associates with the inner biaxin generic er membrane of bacteria, an observation that challenges traditional models in which soluble RNases are proposed to randomly interact with RNAs in the cytosol. Three kinds of potentials are considered: harmonic, Gaussian, and Coulomb-like potentials. Legionellosis in a lung transplant recipient obscured by cytomegalovirus infection and Clostridium difficile colitis. Compared with controls, patients attending exercise-based cardiac rehabilitation led by a registered physiotherapist, demonstrated higher levels of fear-avoidance beliefs at baseline, which decreased over time.

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Human rights group alleges Bush administration and physicians conducted illegal medical research on detainees. Endoscopic papillary balloon dilation may significantly reduce the risk of bleeding compared with endoscopic biliary sphincterotomy in patients with advanced cirrhosis and coagulopathy. The differentiation between a benign or malignant process in these lesions can sometimes be difficult. Flow process for electroextraction of intracellular enzymes from the fission yeast, Schizosaccharomyces pombe. Additional research will focus on primary and secondary prevention strategies. Efficacy of combined inspiratory intercostal and expiratory muscle pacing to maintain artificial ventilation. A retrospective study was based on the medical histories from all patients with EA who underwent surgical repair in our hospital from 1988 through 2012. elegans ina-1 alpha integrin mutants provides the first genetic evidence that migrating neurons require integrins.

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The elastic and viscoelastic properties of pellets and film coatings applied to pellets were studied using Dynamic Mechanical Analysis (DMA). Specifically, we show that drug targets tend to lie upstream of somatic mutations and disease susceptibility germline variants. Risks and benefits of marginal biomass-derived biochars for plant growth. It is now known that even the highly enriched HSC fraction is heterogeneous in terms of lymphopoietic potential. The detection conditions were optimized from the electrochemical properties of estradiol in acidic and alkaline eluents. The daunting tasks of preparing a nation, remedyingyears of under-investment in public health, and promoting cooperative endeavors among agencies unaccustomed to working together cannot be solved merely by money, brief overview training programs, and quick fixes. Diffuse losses from agricultural fields are a major input source for herbicides in surface waters.

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