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Alprasert (Alprazolam)
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Alprasert

Alprasert is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Albiz, Alcicalm, Alpronit, Alzam, Alzep, Alzoft, Ambulax, Anxicalm, Anxigon, Anxofit, Anzal, Azoslip, Benzax, Berest, Cooltime, Ecsit, Flumusa, Hiprazole, Imprax, Notence, Omelam, Orten, Pecalm, Plxna, Pranol, Pronext, Proprazolam, Restam, Somaspas, Tranax, Trazopin, Welnorm, Zeftra, Ziety, Zolorel, Zolorest, Zorest

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Diovan, Rocaltrol, Levitra, Ceftin, Clomid, Cialis, Neoral, Epivir, Cozaar, Anapril, Solbeta, Tramatas, Fedom, Clopod, Alfam, Alenost, Zamadol, Lekuicin,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprasert XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprasert are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Alprasert from your body, which may affect how Alprasert works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Diagnosis of Endometrial-Factor Infertility: Current Approaches and New Avenues for Research. The structures are dominated by a large domain at high radius in the virion, with a smaller domain, which includes the putative RNA-binding site, extending to low radius. The lesion was large, affecting the whole shaft, the scrotum, and the public and inguinal areas. This study was designed to compare the effects of 2 commonly used valved holding chambers (Asthm Yar and Dam Yar) in Iran on bioavailability of salbutamol spray and also spirometric parameters in asthmatic patients. Donor and recipient variables were compared with the epithelial status on the first and third month as well. All of the methods performed well when the diagnostic measures showed product differences in caries in the same direction. Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells. High expression of c-myc in fibroblasts played an important role in the development of LVH in SHR. The pathogenesis, presentation, risk factors, and associated conditions, differential diagnosis, and management of NAION are reviewed. Possible differences between lumbar and thoracic vertebrae were analysed with the Mann-Whitney U test.

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The ability to detect progression using chest X-ray alone appeared very low. Schallhorn is a consultant to Abbott Medical Optics, Inc., Zeiss Meditec AG, and Autofocus Inc. In vitro effects of pancreatic elastase on blood coagulation processes. Here, we summarize recent developments which utilize the potential of microfluidic devices for energy generation. In exclusion experiments, urban doves were more efficient foragers than passerines. The containers have to be designed for a target release in the human gastrointestinal system. Is the echocardiogram an appropriate ECG validity standard for the detection and change in left ventricular size?. clinical state of ICA stenosis is independent of cerebral haemodynamics.

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Rough samples with topography on a scale that is much greater than the micrometer dimensions of the electron interaction volume present an extreme challenge to quantitative electron beam x-ray microanalysis with energy-dispersive x-ray spectrometry. Respiratory infections following haemopoietic stem cell transplantation in children. In this assay, the streptavidin-magnetic nanobeads were conjugated to biotinylated initiators and biotinylated anti-IgG. This is a rare inherited form of ataxia which has not been previously reported in West Indian literature. Subjects in this medical examiner surveillance study were suicides less than 18 years of age. One of these mutants, the nss1 mutant, was characterized in detail. Children aged 6 to 16 had similar rates of diagnosis and hospitalization for all racial/ethnic groups, although African-American children reported wheeze symptoms one-third less often. Mutations of human topoisomerase II alpha affecting multidrug resistance and sensitivity. This in turn can have real cost and efficiency benefits by assisting in the identification of markers that are most likely to be informative, or by highlighting the best candidate genes for study.

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Changing patient perceptions of the side effects of cancer chemotherapy. Participants were 153 outpatients with FM recruited from a hospital pain management unit. Triad studies are important and popular since they are robust in terms of being less prone to false positives due to population structure. 176 women and 176 men with hemochromatosis, matched for year of birth. Absolute hypoxic exercise training enhances in vitro thrombin generation by increasing procoagulant platelet-derived microparticles under high shear stress in sedentary men. Controls demonstrate a lengthening of RTs accompanied by desynchronization of power within the alpha band (approximately 10 Hz) preceding the no-go trial. Recently, neutrophil gelatinase-associated lipocalin (NGAL) was found to be a sensitive biomarker for the prediction of human AKI at a very early stage and the development of AKI after surgery. Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress and reduction of desaturation capacity in mice fed a high-fat diet: Effects on fatty acid composition in liver and extrahepatic tissues. After a new aperture is added to the treatment plan, we use the ASO algorithm to simultaneously optimize aperture weights and leaf positions for the new set of apertures. Cell type-specific green fluorescent protein (GFP) expression in the retina has been achieved in an expanding repertoire of transgenic mouse lines, which are valuable tools for dissecting the retinal circuitry.

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Antiepileptic drug use in a nursing home setting: a retrospective study in older adults. Curcumin, a yellow pigment present in the spice turmeric (Curcuma longa), has been linked with multiple beneficial activities, but its optimum potential is limited by poor bioavailability, in part due to the lack of solubility in aqueous solvents. Upon entry into anaphase, the Cdc14 early anaphase release (FEAR) network initiates dispersal of active Cdc14 throughout the cell. Isolated sleep paralysis (ISP) is a rapid eye movement (REM) sleep parasomnia and has a special meaning in Chinese population. Preheparin LPL mass level correlated negatively with triglyceride (TG), positively with high density lipoprotein-cholesterol (HDL-C), and not at all with total cholesterol (TC) or low density lipoprotein-cholesterol (LDL-C). The sole purpose of an IVC filter is prevention of clinically significant PE. Most of the articles found that PIMs had a statistically significant effect on health care service use, especially on hospitalization, among older adults. Total RNA isolated from each cell population gabapentin neurontin 600 mg tablet was subjected to both reverse transcriptase/polymerase chain reaction and Northern blot analysis using oligonucleotides specific for HLA-E, -F and -G. Soluble complement receptor was detected at the site of C3 deposition and in the urine. Since IL-6 is the major cytokine involved in cellular response to tissue injuries, its relationship with HGF in damaged human liver and kidney is suspected.

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50 Years Ago in TheJournal ofPediatrics: Extrahepatic Biliary Atresia: Comments on the Frequency of Potentially Operable Cases. Mammals have a six-layered neocortex and also exhibit a different morphological organization in the lateral half, or sector, of their pallium than do sauropsids. A novel gelatin-based micro-cavitary hydrogel for potential application in delivery of anchorage dependent cells: A study with vasculogenesis model. The co-culture of wild-type osteoclast precursors with Ccr1(-/-) osteoblasts failed to facilitate osteoclastogenesis. Medical update of diverse Codes comprising anti-alcoholism measures. Birb 796- and SB203580-treated cells were analysed in a genome-wide microarray analysis.

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ARPE19 cells are a good model for studying the internalization mechanisms of LDL and oxLDL in vitro. Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel. We conducted a randomized controlled trial of a self-guided, multimedia stress management and resilience training program (SMART-OP) with a stressed but healthy sample. Space flight resulted in a stimulating effect on cell proliferation, an increase in cell volume and changes in the ionic components of the culture medium. A 55-year-old woman was referred to our hospital for evaluation of a lower abdominal mass. It is argued that absence of Cr causes the higher relative P(i) concentration also observed in animals lacking muscle CK, indicating an important role of the CK system in P(i) homeostasis. The forces applied normally and tangentially to the grip surfaces were measured separately at each plate along with the position of the plates. The ion mobility gas employed was helium for the helium cell (150 mL/min) and nitrogen (80 mL/min) for the T-wave drift tube. Mimicking memory-associated changes in heterochromatin enhances a cellular process thought to underlie long term memory formation, hippocampal long term potentiation, and memory formation itself. The role of anxiety and depression in the physical activity (PA) of patients with COPD is controversial.

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An association between paracetamol use or exposure in different times of life, including gestation and childhood, and asthma has been observed in recent years. Our results at specific time points during the course of healing underscore the role of VEGF in endochondral vs. In particular, such a protocol would increase the effectiveness of a community-based engagement program by instating a formal reminder system for all program members who receive social and/or medical service referrals during outreach in the community. We present evidence that our current ignorance is attributable to the fact that the anterior HF is heavily involved in schizophrenia but has been inadequately examined by schizophrenia investigators. Fleas of small mammals in natural focus of tick-born encephalitis in the Puszcza Bialowieska (National Park).

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