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Alzam (Alprazolam)
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Alzam

Alzam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alzam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alzam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alflux, Alpanol, Alpracon, Alprocalm, Alpron, Alpronit, Alprozam, Alzoax, Alzocum, Alzolam, Alzot, Ambutech, Anlzium, Apsolam, Ateez, Azoslip, Berest, Calmtec, Coolam, Depflu, Ecsit, Eurolam, Faxtin, Fledore, Fluxozam, Fluzolam, Mebaspa, Mentolift, Pecalm, Pizolam, Plaxid, Pranol, Pronext, Propnix, Resolin, Resta, Samitol, Stresnil, Tensyn, Tenzorid, Trustin, Welnorm, Zallpam, Zolax, Zolin, Zoltweet, Zopain

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Mysoline, Avapro, Keflex, Prometrium, Strattera, Idibend, Addcef, Depsolam, Tenase, Supremase, Closprez, Verapamil,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alzam. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

If you have been prescribed Alzam for medical reasons, the best way to avoid a Alzam overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alzam consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alzam XR dosage information

Side effects

The most common side effects associated with Alzam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before taking Alzam, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alzam is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Thermodynamic and kinetic considerations lead to a model where the majority of the adsorbed macromolecule share identical dynamic characteristics under equilibrium conditions. Genetic studies of these organisms have revealed that extended longevity is frequently associated with an increased resistance to stress. Species fall into distinct seasonal groups, within which spatial resource use is more heterogeneous than would be expected by chance at those times when competition for food is most intense. Viral infection in the liver, including hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, is a major health problem worldwide, especially in developing countries. Hepatitis C virus (HCV) is on of the Flaviviridae family of viruses, and is quite heterogeneous, with six major genotypes and more than 100 subtypes.

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In contrast, effectors that regulate Epo-induced differentiation events (e.g. In the presented case, computer assisted surgery (CAS) was used to safely enable a joint-salvaging approach in a modified type 2/3 resection of a grade 2 chondrosarcoma of the os ischium and os pubis. Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6. This method was applied successfully in 2 cases of en plaque sphenoid wing meningiomas with secondary exophthalmia. European collaboration in trials of new agents for children with cancer. All had pathologic N0-1 disease, and none received postoperative radiotherapy. Powerful regression-based quantitative-trait linkage analysis of general pedigrees. The structural effect occurs even when the residue substitution is as much as 7 A from the metal binding site. A chemiluminescence-based assay is developed for the rapid detection of Escherichia coli in fresh produce. Factors associated with pilot fatalities in work-related aircraft crashes--Alaska, 1990-1999.

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The elective resulted in four new, well-received courses and encouraged two participants to pursue careers in academic psychiatry. In 2000, 64 patients tested for AKA and APF (antifilaggrin antibodies) between 1990 and 1993 during evaluation of early symmetric oligoarthritis or polyarthritis (suspected RA) were invited to participate in this non-concurrent cohort study. Carbapenems are potent beta-lactam antibiotics with a broad spectrum of activity against both Gram positive and Gram negative bacteria. Here we describe the transcriptomes of floral and young leaf tissue from Iris fulva generated by massively parallel pyrosequencing. The use of polyethylene glycol (PEG) in the formulation of these agents has the capacity to alter their biological behaviour in such a way as to improve their ability to target tumours. To improve this prognosis, we conducted high-dose chemotherapy with autologous bone marrow rescue in patients with metastatic hepatoblastoma. Sequence comparison demonstrated that the VP92R orthologous protein is present in large yellow croaker iridovirus (LYCIV), but not in rock bream iridovirus (RBIV) or orange-spotted grouper iridovirus (OSGIV). Such categorization may suggest that PD is not clinically significant as other eating disorders.

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The effects of age, gender, and CYP2C9/CYP2C19 genotypes on C:D ratios of VPA were investigated by multivariate analyses (mixed model) including sampling time as covariate. The extracellular matrix protein reelin was identified through its presence in HSC and absence in rMF derived samples. The mice in the two virus infection groups showed strong positivity of MHV antibodies in the serum. An automatic sampler for measurement of dust-deposition rates around fugitive sources. Our results therefore indicate that novel drugs targeted to the major HIV-1 coreceptors will influence HIV replication in the brain, if they cross the blood-brain barrier. Left testicles were subjected to spermatic cord torsion for 4 hours.

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To outline the important contributions of the French physician Petit to the development of ocular biometry. The expression of lysine decarboxylase gene in different parts of Huperzia serrata was analyzed by semi-quantitative RT-PCR, the beta-actin gene was used as internal reference. The work is of high clinical importance given the rapidly growing ageing population and the accompanying costs to health systems globally. It is often initiated by ectopic beats arising from the pulmonary veins and atria. No statistically significant differences were found between groups in time to return of bowel function or hospital length of stay. In membrane flushings, waste water, surface waters and drinking water, levels of the three isothiazolinones were all below the limit of detection. The questions were about personal and job characteristics related to activities in health education.

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Despite these attemps, the lesion continued to grow compressing the posterior fossa structures. Crystallization efficiencies of inorganic polyphosphate oligomers reacted with magnesium and calcium cations using anion-exchange chromatography with particulate formation-laser scattering detector. Inactivation of rifF gives a rifamycin B nonproducing mutant that still accumulates a series of linear polyketides ranging from the tetra- to a decaketide, also detected in the wild type, demonstrating that the PKS operates in a processive manner. The conservative management of dermoid cysts involving both ovaries. Polyethylene glycol hydrogels, as a bioinert control, did not promote any strong responses. Health-Related Quality-of-Life Instruments for Pediatric Patients with Diverse Facial Deformities: A Systematic Literature Review. Although respiratory events during sleep are associated with the occurrence of daytime sleepiness, the differential impact of these events during non-rapid eye movement (NREM) and rapid eye movement (REM) sleep on daytime sleepiness has not been well characterized. Adding an overhead arm extension to the most common standing ITB stretch may increase average ITB length change and average external adduction moments in elite-level distance runners.

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Quadruplet pregnancy: two sets of twins, each occupying a horn of a septate (complete) uterus. Comparisons of the newly determined ryegrass and carrot AFP sequences have led to models suggesting that they might also consist of beta-helices, and indicate that the beta-helix might be used as an AFP structural motif in nonfish organisms. In conclusion, midazolam premedication augments postoperative sedation in this population but does not prolong recovery times. Skin flap closure by dermal laser soldering: a wound healing model for sutureless hypospadias repair. The relationship between nuclear behavior and the histone H1 kinase activity in anesthetized medaka eggs. The excellent agreement of the simulations with experimental data performed up to 6.6 GPa validates the overall approach. Knowledge of the epidemiology of testicular teratomas and associated alpha-fetoprotein (AFP) levels could assist in planning treatment for prepubertal patients suspected of having teratoma of the testis. Absolute refractive indices and thermal coefficients of CaF2, SrF2, BaF2, and LiF near 157 nm. We present a unique case in which involvement of the adjacent ureter in the hernia defect resulted in obstructive uropathy. Our findings suggest that the functions of TRF1 and TRF2 are linked by TIN2.

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This attitude is filtered (Kalman filter) to predict the model position relative to the next image of the sequence. The peer-review process is a turf battle with the ultimate prize of the knowledge, science or doctrine being published. The 45 kDa Arg-specific proteinase and one of the 44 kDa adhesins as well as the 15, 17 and 27 kDa adhesins are processed from the single polyprotein encoded by the gene designated prtR, with all proteins preceded by an Arg or Lys residue within the polyprotein. In selected trials, vibration (60-70 Hz) was applied to the tendon of the biceps and/or anterior deltoid muscles of the dominant arm to distort the proprioceptive information from muscle spindle afferents. Communication V Individual variations in localizations of the zones of specific projections in the cortex of the greater hemispheres in cats and dogs. The purpose of this study was to investigate the impact of 2D and 3D environments on the time taken by novice trainees to learn basic laparoscopic skills and the transferability of the skills learnt in one environment to another. Lesbian identity development: an examination of differences across generations. We report precise energy-resolved measurements of the AD reaction, made with the use of a specially constructed merged-beams apparatus. I/D polymorphism and angiotensin II type 1 receptor genotypes did not relate individually to risk of myocardial infarction or atheroma in univariate or multivariate analysis.

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Induction and characterization of induced pluripotent stem (iPS) cells: a review. The associations among the potential prognostic indicators, the duration of the index episode, and the occurrence of a relapse were analyzed using multivariate Cox regression and logistic regression analysis, respectively. However, these predatory mites are often affected by pesticides and information about the side-effects of these products against these beneficial arthropods is essential to guarantee their efficacy. Additionally, several randomised trials have demonstrated beneficial effects of bone targeted medications in the setting of glucocorticoid-induced osteoporosis. In addition, OCT can detect optic disc parameter changes that cannot be detected by HRT-II. The omptins are multifunctional, and the individual omptins exhibit differing virulence-associated functions. Generation of the items in these scales is described in Studies 1-3. As patients with liver cirrhosis often undergo invasive procedures, we were interested to study whether erythropoietin could improve platelet function in addition to thrombocytopenia.

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Methods for evaluating the potency and efficacy of antioxidants. Low-protein diet impairs vascular relaxation in virgin and pregnant rats. Studies on AHSV replication and pathogenesis have been hampered by the lack of reverse genetics allowing targeted mutation of viral genomes. Metronomic weekly paclitaxel in advanced unresectable esophageal cancer. An open study of the bladder neck support prosthesis in genuine stress incontinence.

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The rigid target specificities of many sites-specific recombinases, however, have limited their adoption in fields that require highly flexible recognition abilities. The activity of respiratory neurons in the ventrolateral medulla was recorded using a perforated patch-clamp technique. Indeed, GR, through its DNA-binding domain, suppresses the binding of C/EBPbeta on the rtER promoter by protein-protein interactions and thereby prevents the enhancer effect of this transcription factor. Thomas Rau, MD: biological medicine and the dynamics of regulation. The presence of genetic effects suggests that unknown genes that influence CAC quantity are yet to be identified. Individuals with TIA were successfully recruited and retained into a RCT. Occurrence of HO is an inevitable postoperative complication after cervical ADR. Among others, the impact of the pancreas and liver surgery extent in relation to the thyroid function remains to be ticlid medication administration elucidated. The goal of the present study is to investigate the patterns of distribution and coexistence of the two endosymbionts, CaGg and Mre, in spore samples of several strains of Gigaspora margarita. This difference is ascribed to poor delineation of the angle of Louis in this age group.

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In all models of experimental and spontaneous colitis examined, ISS-ODN administration ameliorated clinical, biochemical, and histologic scores of colonic inflammation. Pregabalin resulted in shifts from placebo toward greater functional improvement with greater pain relief. Our results provide evidence of a binding through electrostatic interactions between the charged side chains of the protein and the sulphate groups of heparin that does not induce specific conformation of the C-terminal part of IFNgamma. Relation of prothrombin complex factors to cholesterol level in the blood. Reversal of neuronal and cognitive consequences of amphetamine sensitization following chronic treatment with a D1 antagonist. To determine the causes of morbidity, mortality and assess the nutritional status of children under five years, in Koboko refugee camps, Arua District, Uganda.

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Statins have been shown in multiple large trials to reduce the burden of atherosclerotic disease in both middle-aged and elderly patients at elevated risk for coronary events, stroke, and death. A secondary aim of this chapter is to provide practical guidance to health care professionals on how to articulate good lighting objectives to application engineers and designers responsible for the lighting in the NICU. Differently, for the MJJ potentials it is found that such a ratio is about 1:1 which is relevant to that of real proteins. Outcomes included mortality, hospital and surgical intensive care unit (SICU) length of stay, ventilator days and discharge disposition. We extended the model by adding a CSTR equation, to connect the reactor to the biofilm through the boundary conditions. Fast and early root proliferation and long and dense root hairs enhanced uptake of macro- and micronutrients under low soil nutrient availability. Over-expressing transporters associated with antigen processing increases antitumor immunity response in prostate cancer. Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein. The data obtained show that in early pregnancy cephalic index cannot be considered a useful tool in the detection of fetuses at risk for Down syndrome.

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On the effects of temperature, pressure, and dissolved salts on the hydrogen-bond network of water. Mast cells have been implicated in bladder inflammation and pathogenesis. In recent years, great progress has been made in understanding the specific physiological roles of the CRF system. However, their contribution to cerebral amyloid angiopathy-related hemorrhage remains unclear. The buccal administration of ergotamine tartrate (ET) combined with polyvinyl alcohol (PVA) gel brought about higher plasma concentration of ET compared with that of oral administration of capsules in guinea-pigs. In the present study, we comparatively analyze the effects of stain-lyse-and-then-wash techniques periactin drug interactions and lyse-wash-and-then-stain procedures on the detection of both CD55 and CD59 expression on the major peripheral blood (PB) leucocyte subsets, as analyzed by flow cytometry. Oral health in older adults with dementia living in different environments: a propensity analysis. The multi-centre forum for practitioners on GMWs within the greater Jerusalem district. The study points out to narrow relationship between bronchial asthma and allergic rhinitis, where patients with negative decongestion test showed significantly increased grade of bronchial hyperreactivity.

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Axillary thoracotomy versus videothoracoscopy for the treatment of primary spontaneous pneumothorax. TCF x LEF factors are normally repressive but when bound to DNA in a complex with beta-catenin become activators of gene expression. The rates of anesthesia-attributable and anesthesia-contributory cardiac arrest were estimated. This requires Lcd1p, and recruitment of Lcd1p/Mec1p to cdc13-induced damage is abolished by Lcd1p mutations that abrogate its in vivo functions. The lack of zipper-like directional folding does not interfere with triple-helix formation, and when a Gly residue is replaced by Ser to model an osteogenesis imperfecta mutation, the peptide with the N-terminal (GPO)4 domain can still form a good triple helix N-terminal to the mutation site. Expression and localization of cell adhesion molecules in human fetal membranes during parturition. An Examination of Forest Certification Status among Logging Companies in Cameroon.

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A Case of Compartment Syndrome in the Hand Secondary to Intravenous Fluid Application. Elevated expression was also found in cells recovering after heat shock and wounding stress. Assessment of uterine receptivity by the endometrial-subendometrial blood flow distribution pattern in women undergoing in vitro fertilization-embryo transfer. SLC24A5 mutations are associated with non-syndromic oculocutaneous albinism. Pancreatic fistula (PF) is the most common postoperative complication after distal pancreatectomy (DP). The lysozymes may, in general, be a target for the design of a novel type of antibiotics distinct from the beta-lactams which are insensitive to the muramidases. One of the biochemical properties required for stemness to emerge from a population of cells might be the metabolic quiescence that protects organellar DNA from oxidative stress. While the factors and their interaction responsible for compensational smoking are not fully understood, there are data suggesting that a subgroup of smokers may partially compensate for nicotine. Evaluation of 28 human embryonic stem cell lines for use as unrelated donors in stem cell therapy: implications of HLA and ABO genotypes.

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The effect of motional averaging on the calculation of NMR-derived structural properties. This study aimed to report the case of a patient who developed an iliopsoas abscess after a dilation and evacuation for a midtrimester fetal demise. To test the hypothesis that there is a familial predisposition to lumbar disc pain and injury. Its main advantages are simplicity and the lack of need for sample pre-treatment such as derivatization or extraction. CCK-8 was used to observe the toxicity of Zhuhong ointment on HSF. The quality of the medication was measured by its intrinsic value (IV). We have previously shown that inoculation of human chromosome 3 (chr3)/A9 mouse fibrosarcoma microcell hybrids (MCHs) into severely combined immunodeficient (SCID) mice was followed by the regular elimination of certain 3p regions, whereas a 3q region was retained even after prolonged mouse passage. Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. A recombinant fusion protein was constructed consisting of an antihuman pIgR single-chain Fv (scFv) antibody linked to human alpha(1)-antitrypsin (A1AT), an inhibitor of NE.

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Ruthenium-Catalyzed C-H Alkynylation of Aromatic Amides with Hypervalent Iodine-Alkyne Reagents. Because follicular thyroid cancers predominate in iodine deficient and papillary cancers predominate in iodine-replete populations, we have analysed national and regional (former Transvaal) incidences of these cancer types as a surrogate measure of the population iodine nutritional status in South Africa. The resting motor threshold (rMT), the motor-evoked potentials (MEPs), and the controlateral (cSP) and ipsilateral silent periods (iSP) were determined using single-pulse TMS in 15 patients and 15 age-matched controls elavil . This paper uses the theory of interagency information sharing as a lens to determine the benefits, risks, and past experiences of those involved in information sharing. This study demonstrated that decreased basal, but not stimulated, insulin secretion was possibly a major factor associated with secondary SU failure in type 2 diabetic patients.

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Women undergoing mastectomy and breast reconstruction for unilateral breast cancer were recruited for this prospective observational study. Erratum to: Relationship Dynamics and Partner Beliefs About Viral Suppression: A Longitudinal Study of Male Couples Living with HIV/AIDS (The Duo Project). At the end of the second year and before beginning third-year clinical rotations, students take a practical test to demonstrate their competency in the MSK PE. Flexible GaN Light-Emitting Diodes Using GaN Microdisks Epitaxial Laterally Overgrown on Graphene Dots. This finding suggests that the PD/PT ratio of the ginseng saponins may be an important factor in the pharmacological role of red ginseng as a medicinal herb. As such, this method enables the analysis of cell-type specific gene expression using existing large pools of publically available microarray datasets. Erratum: Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response.

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