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Amantadine is used to treat the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) and other similar conditions.

Other names for this medication:
Amantadine, Amantral, Amantrel, Comantrel, Neaman

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Amantadine is an antidyskinetic medicine. It is used to treat Parkinson's disease (sometimes called "paralysis agitans" or "shaking palsy") and its symptoms, including dyskinesia (sudden uncontrolled movements). It may be given alone or in combination with other medicines (eg, levodopa) for Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced. Amantadine is also used to treat stiffness and shakiness caused by certain medicines that are used to treat nervous, mental, and emotional conditions.

Amantadine is also an antiviral medicine. It is used to prevent or treat certain influenza (flu) infections (type A). It may be given alone or together with flu shots. Amantadine will not work for colds, other types of flu, or other virus infections.

This medicine is available only with your doctor's prescription.


Take this medicine with a full glass of water. If you are taking Generic Amantadine to treat influenza A, start taking the medication within 24-48 hours after flu symptoms begin. Do not stop taking it suddenly.


If you overdose Generic Amantadine and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Amantadine dosage information

Side effects

The most common side effects associated with Amantadine are:

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With Denmark as a model we based our assessments partly on a simple calculation model of the exact annual number of neurosurgical trainees or senior registrars and partly used an actuary flow model for calculation. One minor complication (peristomal leakage) occurred in a patient with gastric reflux and atony. We investigated the practical realities of pharmacotherapy for dyslipidemias at a community hospital in Japan. The concentration of ir-inhibin in the peripheral blood may be a useful marker for the examination of testicular activity in stallions being treated with anabolic steroids. Avermectins are final products in the fermentation process with Streptomyces avermitilis. Intracellular trafficking of prohormones and proneuropeptides: cell type-specific sorting and targeting. Dementia is often not coded in hospitals as it is not considered the primary reason for admission. Regional oxygenation in all patients was monitored with FORE-SIGHT Laser Tissue Oximeter. Traumatic rupture of the thoracic aorta is a surgical emergency with a high mortality rate. Although menorrhagia is the most common reproductive tract manifestation of a bleeding disorder, it is not the only manifestation.

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Viable plate counts in aji-narezushi and iwashi-nukazuke were about 6.3-6.6 and 5.7-6.9 log colony-forming units g(-1) respectively. This resulted in a time lag for the attainment of maximum levels of PHAs and rhamnolipids. The cause of the coagulopathy seen with supraceliac aortic cross-clamping (SC AXC) is unclear. Significant mediation effects also indicated that DBT skills use fully mediated the decrease in suicide attempts and depression and the increase in control of anger over time. Doubly transgenic mice (PSAPP) overexpressing mutant APP and PS1 transgenes were examined using antibodies to Abeta subtypes and glial fibrillary acidic protein (GFAP). The cohort was divided into derivation (October 2005 to September 2009) and validation (October 2009 to September 2011) groups.

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Paradoxically, elevated IMTG content in obese and type 2 diabetics has been linked to insulin resistance, highlighting the importance of IMTG pools in physiology and pathology. According to the obtained results, it may be proposed with some caution that the presence of both the -765G allele and the G-765G genotype in the COX-2 gene may confer a susceptibility to an increased risk of recurrent DD in the Polish population. GDP is released primarily by a Ts-induced peptide flip in the nucleotide binding pocket that disrupts hydrogen bonds to the phosphates and repositions the peptide carbonyl so as to sterically and electrostatically eject the GDP. Arthroscopic distal clavicle resection is a safe and effective method of alleviating AC pain. We have shown that significant regional differences in stricture aetiology exist in a large multicentre cohort study. Several lines of studies have suggested the involvement of serotonin transporter (5-HTT) in the pathophysiology of mood disorders. The authors, including academic and community research partners in a community-based participatory research (CBPR) study, reflected together on the use and value of the critical incident technique (CIT) for exploring racial disparities in healthcare for women with breast cancer. The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics.

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A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis. Lamin A precursor induces barrier-to-autointegration factor nuclear localization. Patients were followed up long term with Doppler-echocardiography. Indole-5-carboxylic acids with 3-aryloxy-2-oxopropyl residues in position 1 were previously reported to be potent inhibitors of human cytosolic phospholipase A(2)alpha (cPLA(2)alpha). These findings suggested that subjects with mural plaques and accelerated platelet aggregability, even when asymptomatic, have a poor prognosis due to vascular events. Diagnostic transurethral resection showed four T1, five T2, and seven T3 lesions, all proven solitary by random biopsies. On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: administration of sodium diatrizoate to the horse. In this case it followed an upper respiratory infection with group A Streptococcus. On the basis of the histopathologic findings in our case and the reports from the literature, we recommend radical tumor excision en bloc with all infiltrated adjacent structures. The final section will explore the impact of the change mechanism by analysing the objectives of the organisation.

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The tight junctions were damaged, as evidenced by penetration of lanthanum. EXPERIMENTAL DESING: All premalignant lesions were tested using a length-based PCR assay, which amplified the C-tract region of mitochondrial DNA. This paper describes a mini review which enabled the identification of a suitable methodology to undertake a study about quality in the public health nursing in the Republic of Ireland. Hypothalamic inferior lobe and lateral torus connections in a percomorph teleost, the red cichlid (Hemichromis lifalili). Our results contribute to the better understanding of fish assemblage response to human pressures at a pan-European scale. Effects of glucocorticoids on the trabecular meshwork: towards a better understanding of glaucoma. One month after surgery she had an acute myocardial infarction with cardiogenic shock and was treated with a Palmaz-Schatz stent implantation in the left main coronary artery (that was occluded) and a PTCA of the graft to the right coronary artery. The GCS scores of the menopausal women were significantly positively correlated with their GHQ scores but negatively correlated with their DAS scores.

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The present study recorded the event-related potentials (ERPs) to evaluate brain responses when participants gambled for individual self, for a close friend (relational self), or for the class (collective self). The epidemiological relationship among the strains involved was investigated by analysis of plasmid profile and of chromosomal DNA by pulsed-field gel electrophoresis (PFGE). A portable microkeratome-based anterior corneal surface harvesting device. transplant centers are opposed to using children as living kidney donors. It causes enormous debility and significant mortality, and it costs the American economy hundreds of millions of dollars a year. Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. All the six patients who received tracheotomy were eventually decannulated. arbortristis leaves was investigated for antioxidant activity employing various established in vitro systems, such as lipid peroxidation in liposome, DPPH and hydroxyl radical scavenging, reducing power assay, and iron ion chelation. The patient-, tumor-, and treatment-related variables were recorded and overall survival (OS) and disease specific survival (DSS) were calculated. The synthesis, structure-activity relationships (SAR), X-ray crystallography and pharmacological activity associated with these can you take other cold medicine with zyrtec series of compounds are discussed.

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The mean platinum concentrations in the lesional tissues were 0.98 ppm and 0.5 ppm in the patients administered l-OHP for three and two cycles respectively. Therefore, measuring the hydrocarbon-degrading bacterial populations in the digestive tracts of hydrobionts can be considered an important component of contaminated-site assessment studies. Observations on structure of bone in human mandibular condyles with osteophyte formation. The nature and concentration of the acid, rate of centrifugation and time, number of sequential leachates and the ratio of extractant volume: sample weight have been studied in order to obtain the optimum conditions for extraction. Effect of pasteurized egg and Rosmarinus officinalis supplementation on quality of cryopreserved ram semen. However, the beta-binomial distribution, as with the beta distribution, has a more intuitively satisfactory interpretation and greater flexibility. The distinguishing feature is a universal fluorescence module (UFM), consisting of the eGFP-like Spinach aptamer and a highly active hammerhead ribozyme, which is appended to the RNA of interest (ROI).

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At follow-up, respondents reported a higher proportion of gays and lesbians in their friendship network, more satisfaction with these friendships, higher levels of confidant and appraisal support, less hopelessness, higher self-esteem, and lower levels of depression. The two dyads have similar fluorescent chromophores but differ in their molecular conformations. Acute adverse effects include hyperemesis syndrome, impaired coordination and performance, anxiety, suicidal ideations/tendencies, and psychotic symptoms. The use of this strategy may help correct even slight weight regain and contribute to long-term weight stability. At present, structural determination of most assemblies in different biologically relevant conformations cannot be achieved by a single technique and thus requires an integrative approach that combines information from multiple sources. Single photon emission computed tomography showed hypoperfusion of the right hemisphere in the acute phase. A 53-year-old Japanese male patient had had two retro-auricular skin incisions for tympanomastoidectomy in the postauricular region before implantation of a cochlear implant. Randomised trials with a parallel design on the use of bisphosphonate in myeloma compared with placebo or no treatment as a control group. Magnetic resonance imaging (MRI) was employed for non-invasive analysis of vascular remodeling during follicular maturation in the PMSG/hCG rat ovary model.

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BAL-fluid levels of lactate dehydrogenase (LDH), alkaline phosphatase (AP) and total protein were used as lung damage markers. Management focuses on stabilization and support of respiratory function. An 80-year-old man with a 7 year history of a slowly enlarging, asymptomatic scrotal nodule is presented. We identified the PAF acetylhydrolase gene mutation (G994T) by polymerase chain reaction. Crystallization of monoacylated proteins: influence of acyl chain length. A friend of mine was recently diagnosed with mammary duct ectasia. All had local recurrence or distant metasfases within 15 months after concluding treatment. We evaluated the influence of cryopreservation concentration on the recovery of hematopoietic progenitor cells and the kinetics of hematopoietic recovery of autologous stem cell transplant patients. As this issue is of major therapeutic relevance, published literature considering changes in lithium efficacy over time has been reviewed.

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The specific ET(A)-receptor antagonist BQ-123 (5 x 10(-7) M) caused a significant inhibition of the ET-1-induced positive chronotropic effect in the ring preparations with and without the endothelium. The influence of the chain length is also investigated for a particular location of the sites. The magnetic resonance imaging-based fetal-pelvic index: a pilot study in the community hospital. Low levels of drug resistance in Mycobacterium tuberculosis strains isolated in Guipuzkoa (1993-2001). In the last decade, rapid changes in the healthcare delivery system and socio-political climate have resulted in considerable strain on this relationship. mTOR (mechanistic target of rapamycin) is a pleiotropic kinase found in complex 1 (mTORC1).The mTORC1 pathway governs a response to mitogenic signals with high energy levels to promote protein synthesis and cell growth. These data argue that Salmonella resides intracellularly inside macrophages in the liver and triggers cell death of phagocytes, processes which are involved in disease. Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds. Endoscopic or radiologic evaluation and treatment is the mainstay in the majority of patients, while pharmacologic agents may have a role in patients with refractory bleeding, and those unable to undergo evaluation.

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All medical wards were surveyed three times over a 12-week period from January 1998. The initial dye concentration and the solution pH both significantly affect the adsorption capacity, but the temperature and the cross-linking ratio are relatively minor factors. There were no differences between groups A and B in fiber number and myelin sheath thickness, which were much lower than normal, whereas little myelin sheath regeneration was observed in groups C and D. In 17 cases of inferior meatus antrostomy combined with endoscopic middle meatus antrostomy, one patients relapsed. The side-to-side asymmetry was calculated and expressed as an asymmetry index. The K(A) and K(B) values calculated in the presence and absence of LPS did not differ significantly.

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The longitudinal data revealed four phases of driving disruption: (1) Wait and see, (2) Holding onto a quick fix, (3) No way out, and (4) Resolution and adjustment. A narrow band of the anterior plate bordering these processes shows hexagonally arranged elements. After clinical use, all mini-implants showed surface degradation, plastic deformation, and some fractures. Inducers of autophagy can be identified using rich medium whereas inhibitors are identified under starvation conditions. Radiolabeled cells, containing between 0.7 x 10(-3) Bq/cell and 8.8 x 10(-3) Bq/cell were mixed with unlabeled (i.e., bystander) cells in a ratio of 1:1 and cultured together for 24 h followed by an flow cytometry (FCM) study of their proliferation. Occasionally, resection of the clavicle, jugular vein, or subclavian artery, or a combination of these, was required to eradicate the disease. Low LAA velocity is of limited value in identifying patients who will relapse into AF. MRI pointed out a large, left sylvian arachnoid cyst, agenesia of the olfactory bulbs/tracts arcoxia 60 mg obat untuk apa complex, and hypoplasia of the left olfactory sulcus. The data show a specific temporal pathway involving the sequential and directed accumulation of NHPX in distinct subnuclear compartments, and define a novel mechanism for nucleolar localization. However, a prospective evaluation of cancer patients treated with gemcitabine-based chemotherapy without neoplastic involvement of the thorax and without administration of radiotherapy has not been performed.

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