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Aminidazole (Metronidazole)

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Aminidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

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Also known as: Metronidazole


Aminidazole (metronidazole) is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.

Aminidazole is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Do not use Aminidazole to treat any condition that has not been checked by your doctor.


In the Female. One-day treatment – two grams of Aminidazole, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.


Single oral doses of Aminidazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Aminidazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Aminidazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aminidazole ER dosage information

Side effects

The most common side effects associated with Aminidazole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Aminidazole if you are allergic to metronidazole, secnidazole, or tinidazole, or if:

you recently drank alcohol; or you took disulfiram (Antabuse) within the past 14 days.

Do not take metronidazole during the first trimester of pregnancy. This medicine can harm an unborn baby. Tell your doctor if you are pregnant.

To make sure Aminidazole is safe for you, tell your doctor if you have ever had:

liver disease; kidney disease (or if you are on dialysis); a heart rhythm disorder; Cockayne syndrome (a rare genetic disorder); a stomach or intestinal disease such as Crohn's disease; a blood cell disorder such as anemia (lack of red blood cells) or low white blood cell (WBC) counts; a fungal infection anywhere in your body; or a nerve disorder.

In animal studies, metronidazole caused certain types of tumors, some of which were cancerous. However, it is not known whether these effects would occur in humans. Ask your doctor about your risk.

You should not breastfeed within 24 hours after using Aminidazole. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

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Leukemia cell mobilization with G-CSF plus plerixafor during busulfan-fludarabine conditioning for allogeneic stem cell transplantation. We have shown that AhR knockdown promotes melanoma primary tumorigenesis and lung metastasis in the mouse and that human metastatic melanomas had reduced AhR levels with respect to benign nevi. Separation of two fractions from rabbit anti-BPTI antibody by affinity chromatography. New Dendritic Polydiacetylene Sensor with Good Reversible Thermochromic Ability in Aqueous Solution and Solid Film. After adjustment for years of service and number of dental auxiliaries, no significant differences between the groups were found. Therefore, it was concluded that no summer aestivation occurred. The InBox messaging system is an internal, electronic program used at Mayo Clinic, Rochester, MN, to facilitate the sending, receiving, and answering of patient-specific messages and alerts. We hypothesized that, when compared with an I:E ratio of 1:2, a prolonged I:E ratio of 1:1 would improve respiratory mechanics without reducing cardiac output (CO) during pneumoperitoneum and steep Trendelenburg positioning, both of which can impair respiratory function in robot-assisted laparoscopic radical prostatectomy. Pneumopericardium as a rare complication after esophagopericardial fistula. The concept relies on the successive ligation of oligomers that contain minimal sequence motifs.

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Previous studies have indicated that aging is associated with declines in recollection whereas familiarity-based recognition is left largely unaffected. This toxicity causes damages, particularly to the kidneys (glomerular-nephritis), but does not cause changes in renal function (follow-up 10 years). Characterization of thyroid hormone effects on Na-K pump and membrane potential of cultured rat skeletal myotubes. Use of metronidazole as a probe in the study of human periodontal disease. We observed a decrease in serum bilirubin, alkaline phosphatases (ALP) and IgM in five patients with primary biliary cirrhosis (PBC) treated with Prednimustin (Sterecyt) for 6 months. Site-directed mutagenesis was used to construct 13 individual serine----alanine mutations at conserved residues (3, 16, 18, 25, 26, 57, 71, 76, 102, 105, 127, 211, and 258). The KCC2-dependent developmental increase in the efficacy of GABAA-mediated inhibition is a major determinant of the age-dependent actions of propofol on dendritic spinogenesis. Besides brain imaging, 2p-fMOST could be used in many studies that requires sub-micro resolution or micro resolution imaging of a large sample.

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The pathogenesis of allergic airway inflammation and disease is complex and still not fully understood. If confirmed in a larger sample of surviving obese older adults, these findings may have implications in the clinical approach to obesity in this population. Each of these two species is responsible for various infections. abortusovis growth in the spleen and the liver is controlled by the Ity gene, but also suggest that additional gene(s) regulate the number of bacteria at the site of inoculation. Cellular localization and effects of ectopically expressed hepatitis A virus proteins 2B, 2C, 3A and their intermediates 2BC, 3AB and 3ABC. Nonspecific pain is lamictal starting dose a marker for hypovitaminosis D in patients undergoing evaluation for sleep disorders: a pilot study. Reactance to warnings might be shaped by stereotypical views of smokers. Prospective, comparative, single-masked, interventional clinical study.

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Patients undergoing intestinal resection were compared with those treated with manual reduction alone. Patients with acute myocardial infarction (AMI) with unprotected left main coronary artery (ULMCA) as culprit lesion are a high-risk subgroup with a substantial mortality. Biochemical, anatomical and functional correlates of postnatal development of the capsaicin-sensitive innervation of the rat urinary bladder. PK data about adults and children were available from two different randomized studies of the treatment of malaria with the same artesunate-mefloquine combination regimen. These findings indicated that the patients reacted differently to the same vasoactive drug, and that the papaverine and phentolamine mixture had a stronger effect than papaverine alone, while prostaglandin E1 had the strongest effect on erection. Allergic contact dermatitis caused by timolol with cross-sensitivity to levobunolol. Here we report pulsed-gate transient current spectroscopy and relaxation time measurements of excited states in graphene quantum dots. Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions. An ancestral reconstruction of basic nutritional modes supports numerous transitions from saprobic life histories to plant associated and lichenised modes and a transition from terrestrial to aquatic habitats are confirmed.

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A study of postoperative adjuvant chemotherapy of advanced urinary epithelial cancer. In addition, the hierarchical design of the optimization process helps the proposed tracking algorithm handle long-term occlusions robustly. We suggest that BH4 significantly protects tab cozaar 50 mg price in pakistan against acute renal failure following ischemia reperfusion. This review aims to familiarize the radiologist with the relevant anatomy of the oral cavity, discuss the specific issues that influence prognosis and management at the above subsites, the optimal imaging methods, the role of imaging in accurately staging these cancers and in influencing management. When dealing with cardiac dysfunction, clinicians must consider the underlying pathophysiology, potential myocardial depressant effects of intensive treatments, and the complex interaction with other organ function. The assessment of immunoreaction for acrosin and of vitality of different morphological types of spermatozoa in the same ejaculates, suggested that the antigen was intrinsically absent in abnormal-headed but vital spermatozoa. Two studies tested the hypothesis that Rejection Sensitivity (RS) increases vulnerability to disruption of attention by social threat cues, as would be consistent with prior evidence that it motivates individuals to prioritize detecting and managing potential rejection at a cost to other personal and interpersonal goals. Further, exercise increased the proportion of microglia co-labeled with brain-derived neurotrophic factor (BDNF) in the aged. Compared with usual care, additional homeopathic treatment was associated with significantly higher costs. We have studied eight cases of the adrenals with PPNAD by immunohistochemistry of all steroidogenic enzymes involved in cortisol biosynthesis (P-45scc, 3 beta-HSD, P-450c21, P-45017 alpha, and P-45011 beta) and also by performing in situ hybridization of P-45017 alpha in seven cases in order to localize the sites of specific steroidogenesis in this unique disorder.

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Obesity raises the risk for many chronic diseases and poor health outcomes. Wound healing materials for the dentin and pulp in clinical and roentgenological tests. Clostridium perfringens septicemia is usually fatal without early identification, source control, and antibiotics. Monoclonal gammopathies: new approaches to clinical problems in diagnosis and prognosis. We provide the documentation on the methods, data, and assumptions used to develop two sets of population projections for census tracts in Clark County, Nevada, and discuss specific factors needed to accomplish this task, including the need to bring expert judgment to bear on the task. Our findings on the formation of highly aligned NbS2 nanosheets on graphene give new insight into the formation mechanism of NbS2 and would contribute to the templated growth of various layered materials. We hypothesized this will result in a different rib fracture-associated pediatric mortality rate. The dehiscence of superior semicircular canal is a well-known affection which is able to explain some cases of hearing loss, tinnitus and/or vertigo unexpectedly presenting in adults without previous otologic affections. The assay was then used for TOSV infection diagnosis in 971 clinical samples and for TOSV detection cardizem is what class of drug in 2000 sandflies.

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Although the MG method is technically difficult and requires a lengthy surgery, the technique is considered to be effective for palate closure in terms of speech and maxillary growth. Subcutaneous nodules are associated with cardiovascular events in patients with rheumatoid arthritis: results from a large US registry. Differentiation of hybrid imaginal disc tissue is improved by short term culture in non-hybrid larvae prior to metamorphosis, suggesting that the hybrid larval haemolymph is inadequate to sustain normal imaginal disc growth. This review summarizes how the use of zebrafish has helped understand mechanisms of oligodendrocyte behavior and myelination in vivo and discusses the potential use of zebrafish to shed light on important future questions relating to myelination in the context of CNS development, function and repair. Effect of time and degree of saturation of buffer solutions on artificial carious lesion formation in human tooth enamel. Selective oxidation of methionine residues in Kunitz-type protease inhibitors. Identifying Measures Used for Assessing Quality of YouTube Videos with Patient Health Information: A Review of Current Literature.

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Novel induced mlo mutant alleles in combination with site-directed mutagenesis reveal functionally important domains in the heptahelical barley Mlo protein. Nanoparticle-loaded delivery systems have recently arisen as an exciting alternative to improve targeted anti-glioma drug delivery. Optimization of the in vitro packaging efficiency of bacteriophage T7 DNA: effects of neutral polymers. In detail, FaDu cells alone were used as a control, compared to tumour cells from co-culture, with squamous cell cancer-derived stromal fibroblasts or normal skin human fibroblasts, both in the direct and indirect (insert) systems, adding analysis of side population cells of FaDu culture. Analysis of the promoter for the gene encoding the testis-specific histone H1t in a somatic cell line: evidence for cell-cycle regulation and modulation by distant upstream sequences. Cophylogenetic studies examine the congruence between host and parasite phylogenies. Consequently, the increase of (131)I-MIBG activity, without reaching myeloablative levels, can be recommended for standard treatment of pheochromocytoma and paraganglioma patients. Evidence that SNM1A and SNM1B contribute to ICL repair is mounting, whereas Artemis appears to primarily contribute to non-ICL repair pathways, particularly some double-strand break repair events. Results from the tensile tests showed that scales from Megalops Atlanticus exhibit variations in the elastic modulus as a function of body position. Human airway trypsin-like protease induces mucin5AC hypersecretion via a protease-activated receptor 2-mediated pathway in human airway epithelial cells.

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