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Amotein (Metronidazole)

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Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Aldezol, Anerobia, Avidal, Dirozyl, Efloran, Farnat, Filmet, Flagemed, Flanizol, Geloderm, Grinazole, Medamet, Metazol, Metren, Metrocream, Metrofusin, Metronidazol, Metronidazole, Metronide, Metrovax, Mtronidazole, Nalox, Nizole, Orogyl, Otrozol, Perilox, Pharmaflex, Robaz, Rodogyl, Supplin, Taremis, Tricodazol, Triconex, Vandazole, Zidoval

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Also known as: Metronidazole


Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Amotein. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and loss of balance or coordination.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Amotein are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Assessing cognitive-linguistic abilities in South African adults living with HIV: the Cognitive Linguistic Quick Test. We analyzed the relationship between circulating visfatin levels and anthropometric and metabolic parameters according to central adiposity (total abdominal fat by CT scan). The intervention, delivered by trained allied health professionals, included an initial consultation, three group sessions/individual sessions, three follow-up phone calls, and a final review at 12 months. Medication use was affirmed through tangible medication-taking cues due to the ambivalence in current instructions and labelling. Electrical biasing across the GB is shown to lead to changes at the GB and their observation under an optical microscope.

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Family planning and control of conception, in relation to demographic pressure. Throat swabs were obtained from contacts in whom symptoms developed and were tested for the presence of the H7N9 virus by means of real-time RT-PCR. In patients with frequent PVCs, consistency in hourly PVC frequency throughout the day is an independent predictor of PVC-induced cardiomyopathy. We reviewed the is luvox safe while breastfeeding current literature related to the economics and HR-QOL of NAFLD and found that increased costs and decreased HR-QOL were associated with NAFLD. Recent applications (during 2010-2014) in these areas are presented in tables and some significant findings are highlighted.

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To examine the interplay between high fat and low muscle mass on cardiometabolic risk factors at baseline and in response to exercise in type 2 diabetes. We included all children aged 15 years or less, starting ART (at least three drugs) in the paediatric IeDEA clinical centres in five West-African countries. An sRNA high-throughput sequencing of Arabidopsis thaliana leaf samples infected either with Oilseed rape mosaic virus (ORMV) or crucifer-infecting Tobacco mosaic virus (TMV-Cg) with slightly different symptomatology at two early stages of infection (2 and 4 dpi) was performed. Twenty-two patients with normal body mass index affected by severe obstructive sleep apnea syndrome. The changing brain--insights into the mechanisms of neural and behavioral adaptation to the environment. Sequencing angiosperm plastid genomes made easy: a complete set of universal primers and a case study on the phylogeny of saxifragales. Six patients with either obsessive compulsive disorder, trichotillomania, anxiety, or affective disorders who suffered sexual side effects after treatment with serotonin reuptake blockers were given yohimbine on a p.r.n. Urine and blood samples were collected from 387 children (216 males and 171 females) to examine urinary schistosomiasis and malaria and to determine hemoglobin concentration at Hassoba and Hassoba Buri village in Amibara woreda, Afar region, Ethiopia. An unusual cause of recurrent hemoptysis: tracheopatia osteoplastica.

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