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Anastrozole

Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Pyridium, Alprostadil, Ticlid, Provigil, Rebetol, Persantine, Cetariv, Symbicort, Febrinil, Camezol, Tevafen,

Description

Anastrozole (anastrozole) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Anastrozole is used to treat breast cancer in postmenopausal women.

Anastrozole is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).

Dosage

Usual Adult Dose for Breast Cancer:

Initial dose: 1 mg orally taken once a day Duration of therapy: Until tumor progression (treatment of advanced breast cancer); unknown (adjuvant treatment of early breast cancer) Uses: -Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer; -First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer; -Second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.

Detailed Anastrozole dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anastrozole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Anastrozole can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Anastrozole and other medications

Below are lists of medications that can interact with Anastrozole. These lists do not contain all the drugs that may interact with Anastrozole.

Before taking Anastrozole, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Anastrozole and tamoxifen

Like Anastrozole, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Anastrozole can lower the amount of Anastrozole in your body. This can make Anastrozole less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Anastrozole. However, if recommended by your doctor, it’s fine to take Anastrozole after you’ve finished taking tamoxifen.

Anastrozole and drugs that contain estrogen

Taking Anastrozole with drugs that contain estrogen could make Anastrozole less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Anastrozole.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Anastrozole, talk with your doctor.

Anastrozole and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Anastrozole. However, you should still check with your doctor or pharmacist before using any of these products while taking Anastrozole.

For example, it’s possible that supplements such as red clover or wild yam could make Anastrozole less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Anastrozole.

Anastrozole and foods

There aren’t any foods that are known to interact with Anastrozole. Talk with your doctor to find out if there are any foods you should avoid during Anastrozole treatment.

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Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling. The capacity to form biofilms was evaluated through a catheter-associated biofilm assay. Killer cell immunoglobulin like receptors (KIRs) are a group of activating (aKIRs) and inhibitory receptors (iKIRs) expressed on subsets of lymphoid cells. In all solutions and at both concentrations studied, the mean ondansetron concentration was greater than or equal to 90 percent under all storage and time conditions. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. Increased ROS result in retinal metabolic abnormalities, and these metabolic abnormalities can also produce ROS. Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications. These results confirm that the IFN-gamma molecule is a dimer in solution and indicate that the two sites of the IFN-gamma dimeric molecule which are associated with the biological activity (epitope B22/B27) are fully exposed. Comparative evaluation, assay and model standardisation, greater sharing of information, collaboration and coordination between groups, and rigorous evaluation of existing datasets are steps that can be taken to enable reductions in empiricism over time. In agreement with these changes, GW501516 treatment reversed the increase in DAG and PKCtheta activation caused by palmitate.

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Traumatic Facial Injuries Among Elderly Nursing Home Residents: Never Event or Frequent Occurrence?. To answer this question, the authors evaluated the in vitro IL-6 dependence of the proliferation of myeloma cells from the bone marrow of 13 patients with advanced multiple myeloma (MM) and from the peripheral blood of 13 patients with plasma cell leukemia (seven primary and six secondary cases). Subjects were required to perform actions with everyday objects and to maintain either a meaningful or a meaningless end posture with the object. Developed multiplex real-time PCR offers a fast tool with high sensitivity and specificity for the diagnosis of B. Small valve size and prosthetic patient mismatch are both considered to have harmful effects on residual left ventricular hypertrophy after aortic valve replacement for aortic stenosis. In addition, prior to stream drying the relative colonization rate was higher and drift rate was lower in the temporary streams than in the permanent stream. We conclude that the glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension in our model. However, the effect can you take 40 mg of prilosec might have been merely a change in the inclination of the front teeth. Hyperuricaemia is highly frequent and associated with adverse functional outcomes among Ghanaian stroke patients. Based on our findings, it appears chewing gum during execution of hand movements enhanced the efficiency of hand movements.

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