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Ativan (Lorazepam)

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Ativan is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal. It is used to treat chemotherapy induced nausea and vomiting, as well as for surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. While it can be used for severe agitation, midazolam is usually preferred. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. It can be given by mouth or as an injection into a muscle or vein. When given by injection onset of effects is between one and thirty minutes and effects last for up to a day.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Viramune, Elavil, Precose, Aygestin, Coumadin, Fistide, Unilax, Rosatan, Alfacal, Movibon, Uritin, Ticlop, Clinred,

Also known as: Lorazepam


Ativan belongs to a class of medications called benzodiazepines. These medications work by boosting the activity of gamma-aminobutyric acid (GABA) within your body.

GABA is a neurotransmitter that transmits messages between cells in different parts of your body. Increasing GABA in the body results in a tranquilizing effect that reduces feelings of stress and anxiety.

How long does it take to work?

Benzodiazepines such as Ativan are categorized based on how fast they work. Ativan is classified as having a rapid to intermediate onset (start) of action. It begins to work right away after it’s taken, but its peak effect occurs within 1 to 1.5 hours.


When given intramuscularly, Ativan Injection, undiluted, should be injected deep in the muscle mass.

Injectable Ativan can be used with atropine sulfate, narcotic analgesics, other parenterally used analgesics, commonly used anesthetics, and muscle relaxants.

Immediately prior to intravenous use, Ativan Injection must be diluted with an equal volume of compatible solution. Contents should be mixed thoroughly by gently inverting the container repeatedly until a homogenous solution results. Do not shake vigorously, as this will result in air entrapment. When properly diluted, the drug may be injected directly into a vein or into the tubing of an existing intravenous infusion. The rate of injection should not exceed 2.0 mg per minute.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not use if solution is discolored or contains a precipitate.

Ativan Injection is compatible for dilution purposes with the following solutions: Sterile Water for Injection, USP; Sodium Chloride Injection, USP; 5% Dextrose Injection, USP.


In a medical setting an overdose would be treated quickly.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Ativan is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Ativan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The additive central-nervous-system effects of other drugs, such as phenothiazines, narcotic analgesics, barbiturates, antidepressants, scopolamine, and monoamine-oxidase inhibitors, should be borne in mind when these other drugs are used concomitantly with or during the period of recovery from Ativan Injection.

Extreme caution must be used when administering Ativan Injection to elderly patients, very ill patients, or to patients with limited pulmonary reserve because of the possibility that hypoventilation and/or hypoxic cardiac arrest may occur. Resuscitative equipment for ventilatory support should be readily available.

When Ativan injection is used IV as the premedicant prior to regional or local anesthesia, the possibility of excessive sleepiness or drowsiness may interfere with patient cooperation in determining levels of anesthesia. This is most likely to occur when greater than 0.05 mg/kg is given and when narcotic analgesics are used concomitantly with the recommended dose.

As with all benzodiazepines, paradoxical reactions may occur in rare instances and in an unpredictable fashion. In these instances, further use of the drug in these patients should be considered with caution.

There have been reports of possible propylene glycol toxicity (e.g., lactic acidosis, hyperosmolality, hypotension) and possible polyethylene glycol toxicity (e.g., acute tubular necrosis) during administration of Ativan Injection at higher than recommended doses. Symptoms may be more likely to develop in patients with renal impairment.

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Comparison of non-compression and compression interlocking intramedullary nailing in rabbit femoral shaft osteotomy model. Evaluation of immunostimulating agents used in pulmonologic practice. A case of congenital solitary myofibromatosis occurring in the mandible is presented. This study examined long term swallowing outcomes of a cohort of head and neck cancer (HNC) patients identified at high risk of experiencing significant side effects from cancer treatment and were provided with a proactive PEG. Due to the inhomogeneity of this group of patients and individual combinations of heart defects with or without hemodynamic relevance, preoperative evaluation by a firm pediatric cardiologist is crucial. Observations clozaril 25mg tablets on intra-abdominal pressure and patterns of abdominal intra-muscular activity in man. Cetuximab and anti-EGFR targeted Affibody were conjugated to two different fluorescent dyes (both emitting in the near-infrared) and injected intravenously into 6 athymic mice which were inoculated orthotopically with green fluorescent protein (GFP) expressing human U251 glioma cells.

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Control of burn wound infections by pefloxacin and its silver derivative. Furthermore, these results were corroborated in MC3T3-E1, murine osteoblast cell model. These findings suggest that one of the points of inhibitory action of MPA in the process of angiogenesis may be the suppression of PA activity, and that inhibition of this protease might be useful for reduction of tumorigenic or excessive angiogenesis in vivo. Both BDNF and NGF mRNA levels increased more than 4-fold in the granule layer of the dentate gyrus and for BDNF mRNA also in the pyramidal cells of CA1, while the levels of BDNF mRNA in CA3 increased 2-fold. Therapeutic initiatives for ARPKD face the problem of highly variable cohorts and lack of clinical or biochemical risk markers without clear-cut clinical end points. Following fiber optic examination of the narrowed segment with the patient under anesthesia, the tube was inserted into the trachea using an Airway Scope.

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The association between elevation of the floor of the mouth during sucking tongue on palate and quantitative evaluation can provide insight into the higher participation of the suprahyoid muscles in some participants in both tasks. Longitudinal trends in the treatment of abdominal pain in an academic emergency department. The use of urinary bladder matrix in the treatment of trauma and combat casualty wound care. Apropos of a comparative study of over the counter medication similar to flonase 24 cases of luxation-fractures treated by to-and-fro osteosynthesis or by active protrusive mobilization. All assays could be used to distinguish between positive and negative samples in visible or UV light. Adequate antiretroviral drug potency is essential for obtaining therapeutic benefit, however, the behavioral aspects of proper adherence and readiness to medication, often determine therapeutic outcome. This improvement may allow more widespread use of fibrin glue for operative bleeding. These results suggest that with the acquisition of the putting skill, there are changes in gaze control, characterized by economy in the number of gaze shifts, the development of priority to specific gaze locations, and economy in the allocation of time between preferred gaze locations. Size of the anterior Bolton Index and frequency of the Bolton discrepancy in the anterior tooth segment in untreated orthodontic patients.

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There is little evidence for segregation of competing inflorescence feeders by hostplant species, but some evidence for segregation by habitat type (particularly by shading levels). Heterogeneity of the isolated subunits of the fetal and adult human hemoglobin in solution, detected by XANES spectroscopy. DESIGN/METHODOLOGY/APPROACH: Data were obtained from a survey among 1,354 employees working in 126 teams in 17 organizations. Developmental expression of platelet-derived growth factor and its receptor in the human placenta. A loss-of-function cuv-1 mutation tells us that CUV does not facilitate splicing of pre-mRNA substrates indiscriminately, but differentially effects splicing and expression of genes. Several miRNAs have been shown to be altered in whole cancer tissue compared to normal tissue when quantified by microarray. Grazing by mosquito larvae facilitated leaf decomposition in all treatments. This result adds further neurobiological evidence that long-term phonological representations are more sparsely represented than phonetic representations. An unusually low mealworm removal rate during a morning trial before wasp poisoning heavily influences the results of this side effects of prilosec generic experiment but we have no ecological reason to ignore it.

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Estimating the costs of allocation to male and female functions in a monoecious cucurbit, Lagenaria siceraria. A simplified catheter end hole closing assembly for flush renal angiography. The trial will evaluate effectiveness and costs of a stepped implementation approach that is characterised by tailoring the intensity of implementation activities to the needs of organisations and local barriers for change, in comparison with the generic breakthrough strategy that is usually applied in large-scale improvement projects in the Netherlands. We show that through changes in the oxidation state of the metal, the electron-withdrawing character of the porphyrinato ligand, and the counteranion, the magnitude of the chemiresistive response to ammonia could be improved. Strict observance of radiation safety rules under the responsibility of the head of the company or institution must provide a safe professional environment. The ectopic gland located at the base of the tongue is often asymptomatic but may cause local symptoms such as dysphagia, dysphonia with stomatolalia, upper airway obstruction and haemorrhage, often with hypothyroidism. The scavenger receptor CD36 downmodulates the early inflammatory response while enhancing bacterial phagocytosis during pneumococcal pneumonia.

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Using an iterative eigensolver to compute vibrational energies with phase-spaced localized basis functions. Mothers were recruited prenatally or at the birth of a child to participate in Legacy parenting groups for 3 to 5 years. Local IgA and IgG response to intratracheal immunization with Pseudomonas aeruginosa antigens. Comparative Evaluation of Push Out Bond Strength of a Fiber Post System using Four Different Resin Cements: An In-Vitro Study. Virus neutralization tests were also performed to measure anti-IBDV or anti-H9 AIV neutralizing antibodies in chick embryo fibroblasts. There were numerous instances of doubly labeled neurons stained both with BB and WGA-HRP or RLM, suggesting that uptake of BB combined with UV exposure did not hinder the ability of stained neurons to take up and transport a second tracer. Recent literature highlights the interactions between behavioral and physiological risk factors. A histidine decarboxylase inhibitor can prevent such hypersecretion of acid in the stomach of these animals. Results provide robust evidence that individuals from disadvantaged neighborhoods bear a stigma that influences their prospects in economic exchanges. Oncology nurses perceive patient education in safety as a core element of their professional role and are receptive to advancing their expertise in this area.

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The endocervical canal of first-trimester abortions was dilated by plain mechanical action of a rod-shaped hydrogel body (A-rod) inserted in the cervical canal. Herein, we review the principle, techniques, clinical application, and patient outcomes of image-guided lung tumor ablation. To ascertain whether hospital type is associated with differences in total cost and outcomes for inpatient tonsillectomy. Photosynthetic capacity and stomatal conductance under saturating light intensity and constant water vapor pressure deficit showed almost the same seasonal trend. Shoulder back lumbar pain treated with application with argy wormwood feeleaf volatile oil. Contribution of resident and recruited macrophages to the photodynamic intervention of colorectal tumor microenvironment. To date, there is only one widely accepted clinical guideline for dose modification based on gene status: thiopurine dosing based on TPMT genotype. Interference with angiotensin and sympathetically mediated vasoconstrictor mechanisms probably also contributes to their antihypertensive effects. The results show that compared to a German control group, the MMN response is less robust in Turkish-German children to the German vowel contrast. This review discusses the different FTD clinical syndromes and frontotemporal lobar degeneration (FTLD) pathological correlates as well as new genetic and proteomic findings that have added to our understanding of FTLD pathogenesis.

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