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Cardura (Doxazosin)
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Cardura

Cardura is a selective alpha antagonist. It relaxes the prostate and the area around the bladder, which makes it easier to urinate. It also lowers blood pressure by relaxing blood vessels. The typical starting dose is 1 mg by mouth once a day. Depending on how you respond to the medication, your prescriber may raise your dose, up to a maximum dose of 16 mg once a day.

Other names for this medication:
Alfazosin, Doxacard, Doxapress, Doxazosin, Duracard, Duraten

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Also known as: Doxazosin

Description

Cardura (doxazosin) is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Cardura is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Cardura XL, the extended-release form of this medicine, is used to treat benign prostatic hyperplasia and should not be used to treat hypertension.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 1 mg orally once a day. Maintenance dose: 1 to 16 mg orally once a day.

Usual Adult Dose for Benign Prostatic Hyperplasia:

Initial dose: Immediate-release: 1 mg orally once a day. Extended-release: 4 mg orally once a day with breakfast Maintenance dose: Immediate-release: 1 to 8 mg orally once a day. Extended-release: 4 to 8 mg orally once a day with breakfast. Depending on the patient's symptomatic response and tolerability, the dose may be increased to 8 mg (the maximum recommended dose). The recommended titration interval is 3 to 4 weeks. If switching from immediate-release to extended-release tablets, therapy should be initiated with the lowest dose (4 mg once daily). Prior to starting therapy with Cardura extended-release tablets, the final evening dose of immediate-release tablets should not be taken. If Cardura extended-release tablets are discontinued for several days, therapy should be restarted using the 4 mg once daily dose.

Usual Geriatric Dose for Hypertension:

Initial dose: 0.5 mg orally once a day.

Detailed Cardura dosage information

Overdose

If you overdose Cardura and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cardura are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Cardura if you are allergic to doxazosin or similar medicines such as alfuzosin (Uroxatral), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin).

To make sure Cardura is safe for you, tell your doctor if you have:

a blockage in your digestive tract (stomach or intestines); severe constipation; liver disease; or low blood pressure.

Cardura can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Cardura before surgery unless your surgeon tells you to.

It is not known whether doxazosin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether doxazosin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Cardura.

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Medial pathway patterns of the right retromesenteric plane: anatomical investigation using MDCT in patients with acute pancreatitis and pyelonephritis. The results partially support Taiwan Poison Control Center guidelines for treating the hemorrhagic-type venom snakebite. The primary adaptation required was to reduce nurse caseloads from 25 to 20 active clients. A single step protein precipitation with acetonitrile was used for sample preparation. A number of other trace elements have also been found to have impact, particularly on the disease of dental caries. Molecular cloning and expression of two distinct cDNA-encoding heparan sulfate proteoglycan core proteins from a rat endothelial cell line.

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