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Coumadin (Warfarin)
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Coumadin

Coumadin is a vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.

Other names for this medication:
Jantoven, Lycobion, Sofarin, Uniwarfin, Warfarin

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Also known as: Warfarin

Description

Coumadin target is the treatment of blood clots in arteries and veins (venous thrombosis) and in the lung (pulmonary embolism), strokes, heart seizures. It is also taken by patients with prosthetic heart valves. Coumadin is acting by making inability of blood to form the clots. It is anticoagulant ('blood thinner'). Generic name of Coumadin is Warfarin. Coumadin is also known as Warfarin sodium, Warf, Jantoven, Marevan, Waran. Brand name of Coumadin is Coumadin.

Dosage

Take Coumadin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take warfarin in larger or smaller amounts or for longer than your doctor tells you to.

Take this medicine at the same time every day, with or without food. Never take a double dose.

Coumadin can make it easier for you to bleed. Seek emergency help if you have any bleeding that will not stop.

You will need frequent "INR" or prothrombin time tests (to measure your blood-clotting time and determine your warfarin dose). You must remain under the care of a doctor while taking Coumadin.

If you receive Coumadin in a hospital, call or visit your doctor 3 to 7 days after you leave the hospital. Your INR will need to be tested at that time. Do not miss any follow-up appointments.

Tell your doctor if you are sick with diarrhea, fever, chills, or flu symptoms, or if your body weight changes.

You may need to stop taking Coumadin 5 to 7 days before having any surgery, dental work, or a medical procedure. Call your doctor for instructions.

Wear a medical alert tag or carry an ID card stating that you take warfarin. Any medical care provider who treats you should know that you are taking this medicine.

Store at room temperature away from heat, moisture, and light.

Detailed Coumadin dosage information

Overdose

If you overdose Coumadin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Coumadin overdosage: round, small, red spots under the skin, painful menstruation, bruising, minor cuts bleeding, gums bleeding, bloody stools, heavy bleeding.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Coumadin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Coumadin if you are allergic to its components. Do not take Coumadin if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Coumadin if you suffer from or have a history of heart infection, stomach ulcer or bleeding, anemia, hemophilia, fluid or swelling around your heart, blood clot or aneurysm in the brain. Do not take Coumadin if you are under 18 years. It can be taken by adults over 18 years. Do not take this medicine if you are taking non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen (Naprosyn, Aleve), indomethacin, diclofenac (Voltaren), piroxicam (Feldene), ibuprofen (Advil, Motrin), celecoxib (Celebrex). Be careful with Coumadin if you suffer from or have a history of high blood pressure, cancer, seizure disorder, polycythemia vera, celiac sprue, heart failure, thyroid condition, kidney or liver disease, severe diabetes. Elderly people should be very careful with Coumadin and its dosage. Be careful with Coumadin if you are going to have a surgery or take antibiotics. Avoid food with large amounts of Vitamin K (green vegetables, liver and other) and cranberry. Avoid food sport activities. Avoid alcohol and smoking cigarettes while taking Coumadin because it can cause side effects. Do not stop taking Coumadin suddenly.

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Beginning with the fundamental relation between MRI signal and tissue magnetic susceptibility this review covers the reconstruction of magnetic field maps from multi-channel phase images, background field correction, and provides an overview of state of the art QSM solution strategies. The role of the masseter muscle in craniofacial adaptations to altered vertical dimension was determined by detaching and re-attaching the insertion of the masseter muscle in one group of experimental animals. Repair of DNA damage induced by the mycotoxin alternariol involves tyrosyl-DNA phosphodiesterase 1. We have examined the contributions of Interleukin 4 (IL-4), IL-5, and other stimuli to the expression of Immunoglobulin G1 (IgG1) and IgE in murine B lymphoblasts activated with anti-Ig. Galectin-1 suppresses methamphetamine induced neuroinflammation in human brain microvascular endothelial cells: Neuroprotective role in maintaining blood brain barrier integrity. Autogenic drainage (AD), slow expiration with glottis opened in lateral posture (ELTGOL), and temporary positive expiratory pressure (TPEP). Artificial disc and vertebra system: a novel motion preservation device for cervical spinal disease after vertebral corpectomy. Isolation of new peptides related to beta-melanocyte-stimulating hormone. Differences in early callose deposition during adapted and non-adapted powdery mildew infection of resistant Arabidopsis lines.

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A new species of Cales (Hymenoptera: Aphelinidae) parasitizing Bemisia pongamiae (Takahashi) (Hemiptera: Aleyrodidae) in Taiwan, with a key to world species of the Cales spenceri-group. The length of hospital stay and postoperative recovery are significantly shortened compared to standard cholecystectomy. Applying ISO 16840-2 Standard to differentiate impact force dissipation characteristics of selection of commercial wheelchair cushions. By providing the assessor with evidence drawn from multiple modalities, some of which provide converging patterns and some of which yield divergent results, a multimethod assessment compels the assessor to engage this evidence more deeply. Total RNA was isolated from osteogenesis imperfecta cells in culture, cDNA was synthesized using alpha 1(I) and alpha 2(I) specific primers, and fragments of cDNA suspected to harbor the mutation were amplified by the polymerase chain reaction technique and then cloned in M13 vectors. Tube technique was used for comparison with the microplate method for 100 samples. We report a high-throughput platform for delivering large cargo elements into 100,000 cells in 1 min. Modulation of arabinosylcytosine metabolism by arabinosyl-2-fluoroadenine in lymphocytes from patients with chronic lymphocytic leukemia: implications for combination therapy. Similar rates of sugar consumption (4.44 mM glucose h(-1) and 6.66 mM xylose h(-1)) were observed suggesting this strain could use either glucose or xylose as the substrate and it has a similar capability to degrade these two sugars.

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