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Coumadin (Warfarin)

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Coumadin is a vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.

Other names for this medication:
Jantoven, Lycobion, Sofarin, Uniwarfin, Warfarin

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Also known as: Warfarin


Coumadin target is the treatment of blood clots in arteries and veins (venous thrombosis) and in the lung (pulmonary embolism), strokes, heart seizures. It is also taken by patients with prosthetic heart valves. Coumadin is acting by making inability of blood to form the clots. It is anticoagulant ('blood thinner'). Generic name of Coumadin is Warfarin. Coumadin is also known as Warfarin sodium, Warf, Jantoven, Marevan, Waran. Brand name of Coumadin is Coumadin.


Take Coumadin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take warfarin in larger or smaller amounts or for longer than your doctor tells you to.

Take this medicine at the same time every day, with or without food. Never take a double dose.

Coumadin can make it easier for you to bleed. Seek emergency help if you have any bleeding that will not stop.

You will need frequent "INR" or prothrombin time tests (to measure your blood-clotting time and determine your warfarin dose). You must remain under the care of a doctor while taking Coumadin.

If you receive Coumadin in a hospital, call or visit your doctor 3 to 7 days after you leave the hospital. Your INR will need to be tested at that time. Do not miss any follow-up appointments.

Tell your doctor if you are sick with diarrhea, fever, chills, or flu symptoms, or if your body weight changes.

You may need to stop taking Coumadin 5 to 7 days before having any surgery, dental work, or a medical procedure. Call your doctor for instructions.

Wear a medical alert tag or carry an ID card stating that you take warfarin. Any medical care provider who treats you should know that you are taking this medicine.

Store at room temperature away from heat, moisture, and light.

Detailed Coumadin dosage information


If you overdose Coumadin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Coumadin overdosage: round, small, red spots under the skin, painful menstruation, bruising, minor cuts bleeding, gums bleeding, bloody stools, heavy bleeding.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Coumadin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Coumadin if you are allergic to its components. Do not take Coumadin if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Coumadin if you suffer from or have a history of heart infection, stomach ulcer or bleeding, anemia, hemophilia, fluid or swelling around your heart, blood clot or aneurysm in the brain. Do not take Coumadin if you are under 18 years. It can be taken by adults over 18 years. Do not take this medicine if you are taking non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen (Naprosyn, Aleve), indomethacin, diclofenac (Voltaren), piroxicam (Feldene), ibuprofen (Advil, Motrin), celecoxib (Celebrex). Be careful with Coumadin if you suffer from or have a history of high blood pressure, cancer, seizure disorder, polycythemia vera, celiac sprue, heart failure, thyroid condition, kidney or liver disease, severe diabetes. Elderly people should be very careful with Coumadin and its dosage. Be careful with Coumadin if you are going to have a surgery or take antibiotics. Avoid food with large amounts of Vitamin K (green vegetables, liver and other) and cranberry. Avoid food sport activities. Avoid alcohol and smoking cigarettes while taking Coumadin because it can cause side effects. Do not stop taking Coumadin suddenly.

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Quantification and molecular analysis of cathepsin D in breast cyst fluids. The authors evaluated the feasibility of 3 regions of the occiput as sites for occipitocervical fixation by examining bone mineral density at these locations. Levels of malondialdehyde (MDA) plus 4-hydroxyalkenal (4-HDA), and carbonyl content in the proteins were measured as indices of oxidative damage to lipids and proteins, respectively. Adaptive variation in growth rate: life history costs and consequences in the speckled wood butterfly,Pararge aegeria. The poliovirus epitope was accessible to monoclonal antibody C3 at the cell surface. We report two cases referred to our department with different characteristics, background, diagnostic modalities and different courses. With the exception of e-PTFE, 4-0 sutures had greater tensile strength than did 5-0 sutures. Fibroblasts: important producers and targets of inflammatory prostaglandins in the lungs.

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Vagal vasodilatory mechanisms in the pig bronchial circulation preferentially involves sensory nerves. Mid-infrared mode-locked pulse generation with multilayer black phosphorus as saturable absorber. Tadpoles of Rana temporaria which have been raised in an artificial pond prey in the experimental situation shown in Fig. We analyzed the transcriptome of miR-124 expressing and nonexpressing cells from wild-type and mir-124 mutants. Introducing an appropriate non-dimensionalization for the mathematical relations describing flap-gliding flight, results and findings of generally valid nature are derived. The course of all mycoses in AIDS patients is quite different from the course of the same mycoses complicating other diseases. The Finnish Funding Agency for Technology and Innovation (TEKES), Project number 40011/08. The presence of unphosphorylated PKCgamma in HT29 cells, and its complete absence in Caco2 cells demonstrates a cell type-dependent differential coupling of Thr(514)-phosphorylation with de novo synthesis of PKCgamma in colon cancer cells. Platelet monoamine oxidase activity predicts alcohol sensitivity and voluntary alcohol intake in rhesus monkeys.

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Beginning with the fundamental relation between MRI signal and tissue magnetic susceptibility this review covers the reconstruction of magnetic field maps from multi-channel phase images, background field correction, and provides an overview of state of the art QSM solution strategies. The role of the masseter muscle in craniofacial adaptations to altered vertical dimension was determined by detaching and re-attaching the insertion of the masseter muscle in one group of experimental animals. Repair of DNA damage induced by the mycotoxin alternariol involves tyrosyl-DNA phosphodiesterase 1. We have examined the contributions of Interleukin 4 (IL-4), IL-5, and other stimuli to the expression of Immunoglobulin G1 (IgG1) and IgE in murine B lymphoblasts activated with anti-Ig. Galectin-1 suppresses methamphetamine induced neuroinflammation in human brain microvascular endothelial cells: Neuroprotective role in maintaining blood brain barrier integrity. Autogenic drainage (AD), slow expiration with glottis opened in lateral posture (ELTGOL), and temporary positive expiratory pressure (TPEP). Artificial disc and vertebra system: a novel motion preservation device for cervical spinal disease after vertebral corpectomy. Isolation of new peptides related to beta-melanocyte-stimulating hormone. Differences in early callose deposition during adapted and non-adapted powdery mildew infection of resistant Arabidopsis lines.

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The embryonic expression of Hox 2.1 in neural tissue is compared with that of Hox 3.1, which also shows anteroposterior restricted domains of gene expression. This will require new ways of thinking that go beyond the epidemiologic transition theory. Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. The results are consistent with a bifunctional organization of EG2, in which the 118-kDa enzyme is composed of a 51-kDa catalytic domain and is there a difference between zyrtec and generic a highly antigenic 43-kDa substrate-binding domain. MK-801 was administered 30 min before the training session on Day 1 to look for anterograde amnestic effects, immediately after training to look for retrograde amnestic effects, and before the training or test session, or both, to look for state-dependence effects. Objective evaluation of the intensity of pain sensations by an evoked potentials method. Our objective was to test the hypothesis that, following FLA for TTTS, iPPROM may be prevented by placement of an absorbable gelatin CAP.

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A new species of Cales (Hymenoptera: Aphelinidae) parasitizing Bemisia pongamiae (Takahashi) (Hemiptera: Aleyrodidae) in Taiwan, with a key to world species of the Cales spenceri-group. The length of hospital stay and postoperative recovery are significantly shortened compared to standard cholecystectomy. Applying ISO 16840-2 Standard to differentiate impact force dissipation characteristics of selection of commercial wheelchair cushions. By providing the assessor with evidence drawn from multiple modalities, some of which provide converging patterns and some of which yield divergent results, a multimethod assessment compels the assessor to engage this evidence more deeply. Total RNA was isolated from osteogenesis imperfecta cells in culture, cDNA was synthesized using alpha 1(I) and alpha 2(I) specific primers, and fragments of cDNA suspected to harbor the mutation were amplified by the polymerase chain reaction technique and then cloned in M13 vectors. Tube technique was used for comparison with the microplate method for 100 samples. We report a high-throughput platform for delivering large cargo elements into 100,000 cells in 1 min. Modulation of arabinosylcytosine metabolism by arabinosyl-2-fluoroadenine in lymphocytes from patients with chronic lymphocytic leukemia: implications for combination therapy. Similar rates of sugar consumption (4.44 mM glucose h(-1) and 6.66 mM xylose h(-1)) were observed suggesting this strain could use either glucose or xylose as the substrate and it has a similar capability to degrade these two sugars.

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Different types of dynamic curves, reflecting the level of O-antigen in the biological fluids of patients with acute Sonne dysentery and characteristic of different clinical forms of the disease, have been established. Vasoactive intestinal peptide stimulates proenkephalin A mRNA expression in bovine adrenal chromaffin cells. Enhancing monoclonal antibody activity in chronic lymphocytic leukemia. Nematodes parasitizing Trachurus trachurus (L.) and Boops boops (L.) from Algeria. Toll-like receptors (TLRs) are innate immune molecules that can induce anti-viral responses, therefore the application of TLR ligands as prophylactic agents in chickens is gaining more attention. This way, repeating the exact same optical drive twice, we find consistent or inconsistent responses depending on the pump parameter and we relate the kind of response to strong and weak chaos.

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Knowledge, attitude and practices related to visceral leishmaniasis among residents in Addis Zemen town, South Gondar, Northwest Ethiopia. Autogenous semitendinosus tendon with the tibial attachment preserved has been used for the medial/posteromedial compartment reconstruction. Enterococcus faecalis inhibits superantigen toxic shock syndrome toxin-1-induced interleukin-8 from human vaginal amaryl brand name epithelial cells through tetramic acids. To clarify whether RNA-directed DNA methylation (RdDM) can repress the transcriptional activity of the S44 transgene locus, we introduced several RdDM constructs targeting the transgene promoter. One thousand three hundred twenty-four active duty soldiers completed a self-report survey assessment that included measures of the 4 different stigma perceptions, indices of mental health symptoms, receipt of mental health treatment, and whether they had dropped out of treatment before it was completed. NH M phi stimulated at the Mac-1 receptor demonstrated higher DNA synthesis than control NH M phi although TBH M phi stimulated at this receptor and control TBH M phi failed to show any differences.

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