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Epivir (Lamivudine)
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Epivir

Epivir is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.

Other names for this medication:
Abamune, Combivir, Duovir, Emduo, Emtri, Haptavir, Hepavud, Hepitec, Hepravir, Hivir, Ladiwin, Lamidac, Lamistar, Lamivir, Lamivox, Lamivudine, Lamostad, Lamuvid, Lavir, Lazid, Lmivir, Nevilast, Odivir, Retrolam, Shanvudin, Stadin, Stavex, Tenola, Tenolam, Tenvir, Trimune, Trioday, Viramid, Virolam, Virolis, Zidolam

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Also known as: Lamivudine

Description

Epivir is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Epivir is not a cure for HIV or AIDS. Epivir is used to treat chronic hepatitis B. Epivir works by blocking the ability of the hepatitis B virus to multiply and infect new liver cells. Epivir is also known as Lamivudine, Lamivir, Zeffix, Heptovir. Generic Name of Epivir is Lamivudine. Brand names of Epivir are Epivir, Epivir HBR.

Dosage

This section provides information on the proper use of a number of products that contain lamivudine. It may not be specific to Epivir A/F. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Epivir® and Epivir-HBV® both contain the same medicine, but Epivir® has more medicine in each tablet or dose of liquid. Use only the brand of this medicine that your doctor prescribed. If you have HIV or AIDS, you need to use Epivir®. If you have hepatitis B but you do not have HIV or AIDS, you can use Epivir-HBV®.

Your doctor may want to test you for HIV before you start using Epivir-HBV® and during your treatment. Your medicine may need to be changed based on these test results.

It is important to take Epivir® as part of a combination regimen. Take all of the medicines your doctor prescribed at the right time of day. This will make your medicines work better.

Keep using lamivudine for the full time of treatment, even if you or your child begin to feel better. Do not stop using it without checking first with your doctor. When your supply of the medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of the medicine.

If you are using the oral liquid, use a specially marked measuring spoon, dosing syringe, or medicine cup to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (solution or tablets): For treatment of hepatitis B infection: Adults—100 milligrams (mg) once a day. Children 2 to 17 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 3 milligrams (mg) per kilogram (kg) of body weight per day. The doctor may increase your dose as needed. However, the dose is usually not more than 100 mg per day. If your child cannot swallow the tablets, he or she may take the oral liquid. Children younger than 2 years of age—Use and dose must be determined by your doctor. For treatment of HIV infection or AIDS: Adults—300 milligrams (mg) once a day or 150 mg 2 times a day. Children 3 months of age and older— Solution: Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight taken 2 times a day, or 10 mg per kg once a day. The doctor may increase your dose as needed. However, the dose is usually not more than 300 mg per day, taken with other HIV medicines. Tablets: Dose is based on body weight and must be determined by your doctor. The dose is usually 150 to 300 mg per day. If your child weighs 14 kg or more, it is preferred that he or she take the scored tablet. Children younger than 3 months of age—Use and dose must be determined by your doctor.

Note: Patients that require treatment for both hepatitis B and either AIDS or HIV should follow the dosing schedule for HIV or AIDS.

Overdose

If you overdose Epivir and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lamivudine dosage information

Side effects

The most common side effects associated with Epivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid taking other medications that contain an ingredient called sorbitol, often used as a sweetener in liquid medicines. Ask your pharmacist if you are not sure a medicine contains this ingredient.

Using Epivir HBV will not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

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Subsequent derivation of prediction rules was established with the aim of analyzing molecular structures and mechanisms by means of 114 residue compositions for venom toxins. However, qualitative methods are also of potential value in furthering our understanding of obsessive-compulsive disorder heterogeneity by allowing for open-ended exploration of the obsessive-compulsive disorder experience and correlating identified subtypes with patient narratives. For patients with schizophrenia, anhedonia was significantly related to premorbid functioning. As found by chemical cross-linking beta H-endorphin bound to both, the 65- and 75-kDa molecular mass forms of S protein. So, the present study attempts to investigate the content of total polyphenols, flavonoids, antioxidant activity and estimate the rough content of amarogentin, swertiamarin and mangiferin from different species of Swertia from Nepalese Himalayas. Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: a systematic review. Further, a negative relationship between concentration of polyphenols and the height of the species was found, independent of their ability to fix N2.

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Recent contributions to our knowledge of the mechanisms underlying hyperalgesia and sensitization are reviewed. Our experiments demonstrate that expression of the AP-2 gene in HeLa cells is not elevated significantly by TPA or by a calcium ionophore and is not enhanced at all by agents that increase intracellular cAMP concentration. Finally, we will consider the potential benefits of a countermeasure, such as napping, in minimizing the neuroendocrine and immune stress and cardiovascular risk imposed by shift work. We show that the rose ortholog of AGAMOUS (RhAG) is differentially expressed in double flowers as compared to simple flowers. We examined the natural killer (NK) activity of pediatric patients with acute lymphoblastic leukemia (ALL) in remission by using several methods, including a newly established single cell assay. Sleep EEG variables were not significantly correlated to the Body Mass Index. Primary dural invasion by diffuse large B-cell lymphoma is extremely rare, with only a few cases reported in the literature. Social and behavioural sciences at the Massachusetts College of Pharmacy and Allied Health Sciences. The cancer survivors scored significantly lower in the cognitive domains of executive functioning, working memory, and divided attention, reflecting potential dysfunction in frontal-subcortical brain regions. Flow-mediated dilation at 90 seconds and after nitoglycerin significantly improved at 4 hours and at 1 month after drinking both kinds of juices, without significant difference between the two groups.

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Treatments of this disease include agents directed at allergic mediators such as leukotriene modifiers and corticosteroids, although this does not necessarily signify that an IgE-dependent mechanism can be ascribed. The scores were compared to those of a control group of 68 subjects attending the hospital for routine examinations or as accompanying persons. A 55-amino acid segment, normally present between residues 241 and 295 of the 348-residue gene I protein of the filamentous bacteriophage f1, acts as an internal signal sequence for gene I protein or, when present in fusion proteins, for EcoRI endonuclease or alkaline phosphatase. Three observations indicate that the borders of the individual disc primordia lie very close to each other, separated by few if any non-disc cells.First, the frequency of mosaicism within each disc indicates large primordia, of similar magnitude to the distances between the centres of adjacent primordia.Second, very few XX/XO-borders cut between adjacent discs without also cutting into one or the other disc.Third, sturt distances between points on adjacent discs are often much smaller than distances measured within individual discs. The base excision repair (BER) pathway is the major DNA repair pathway for oxidative DNA damage and genetic variation associated with impaired BER might thus increase a risk of CRC. Urinary and fecal excretion of porphyrins and their precursors in leukemia patients. Neutrophil elastase plays a crucial role in the development of acute lung injury (ALI) in patients with systemic inflammatory response syndrome (SIRS). SEM has been growing in various disciplines as well as in rehabilitation research. Reviewing previous BOS studies to explore restrictive spirometric cases and joint projects via groups like the International Pediatric Lung Transplant Collaborative will be the way forward to solve this pressing problem.

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An upper limit on the contribution of accreting white dwarfs to the type Ia supernova rate. 3D printing of layered brain-like structures using peptide modified gellan gum substrates. In the conditioned place preference test, the 2-week HFD-intake group showed preference for HFD and had increased expression of a marker for reactive astrocytes, glial fibrillary acid protein (GFAP), in the hypothalamus. Plantain native starch was hydrolysed with sulphuric acid for twenty days. Chinese nonbelievers studied by Jing are not very different than nonbelievers in other cultures. Assessing serum hemoglobin levels without venipuncture: accuracy and reliability of Pronto-7 noninvasive spot-check device. Incidence of deep vein thrombosis in major adult spinal surgery. Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture.

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Administration of 6.5 nmoles of SP(1-7) produced a transient decrease in reaction time at 1 min after injection with a return to above control values by 5 min. We tested the effectiveness of offering home fecal immunochemical tests (FITs) during influenza vaccination clinics to increase colorectal cancer screening (CRCS). Pseudopseudohypoparathyroidism vs progressive osseous heteroplasia in absence of family history. Oligonucleotide linker insertion mutagenesis of the plasmid DNA from this recombinant clone was used to confirm that expression of the 100-kDa protein correlated with the heme-hemopexin-binding activity. All eligible studies measured blood ARA levels as an indicator of exposure.

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Response to Overcoming the Barrier to Implementing Authentic Research Experiences through Faculty Mentorship: The ASCB Mentoring in Active Learning and Teaching (MALT) Program Is Designed to Facilitate Vision and Change-Inspired Teaching Practices. As a minimally invasive procedure, wrist arthroscopy provides the advantages of accurate, direct visual inspection of intra-articular structures for diagnostic purposes and dramatically reduced morbidity for surgical treatment of certain disorders. The data convincingly demonstrate the broad perspective of stereo- and regiospecifically generating cyclized peptide pharmaceuticals with significantly enhanced therapeutic potential. The spectral and spatial filtering originates from scattering cancellation localized at the nanorod due to the cavity and nanorod exhibiting opposite effective dipole moments. Granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3), or a combination of both growth factors were added weekly to normal human long-term bone marrow cultures (LTBMC). Electroporation is the formation of permeabilizing structures in the cell membrane under the influence of an externally imposed electric field. The admission head CT showed small subcortical haemorrhage in the left temporal lobe. We aimed to study the prevalence OAC discontinuation in patients who presented with acute ischemic stroke as well as the outcomes of these strokes. Low maternal education and socio-economic status were associated with household food insecurity in children under five with diarrhoea in Bangladesh.

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Its prognostic implications are less well defined in patients with coronary artery disease. No effect of Valsalva maneuver or Trendelenburg angle on axillary vein size. Although several polypeptides are present in our most purified extracts, an antiserum against polypeptides in the range of 80 kD completely blocked AChR aggregation by soluble extracts of the electric organ. They can be classified as defects of signalling through CD40 causing both a humoral immunodeficiency and a susceptibility to opportunistic infections, or intrinsic defects in B cells of the mechanism of CSR resulting in a pure humoral immunodeficiency. Collapsing Focal Segmental Glomerulosclerosis in a Patient with Acute Malaria. The mechanism of the suppression of HLA-DR antigen expression is unlikely to be due to the free radical scavenging.

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More research is required to establish the efficacy and safety of potential social media-based interventions and ethical standards and protocols to ensure that such interventions are delivered safely need to be developed and implemented. Please see related article: http://www.biomedcentral.com/1741-7015/12/231. The method was evaluated over an 8-month period and has thus far identified 2 cases of phaeochromocytoma, 1 case of neuroblastoma and 2 of carcinoid tumour. Clinical Implications Associated With the Posttranslational Modification-Induced Functional Impairment of Albumin in Oxidative Stress-Related Diseases. Using a proteomic workflow combining membrane fractionation, SDS-PAGE separation and nanoUPLC-MS(E) technology, we identified 673, 679 and 682 non-redundant proteins from mouse iPSC, ESC and TTF membrane fractions, respectively. Any of the above mechanisms can result in impairment of desmosomal function with subsequent acantholysis.

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There is no data on long-term outcome in this cohort of patients. For the general practitioner, but particularly for travel medicine practitioner and pediatricians, these clinicoepidemiological considerations should be taken in mind in the differential diagnosis when assessing children returning from travel to brucellosis endemic areas. Complete descriptions of every stage are provided and illustrated, and their usefulness for species comparison, taking into account our uneven knowledge of morphologically immature stages of this subgenus, is indicated. The region of the protein most strongly conserved structurally also shows the highest amino acid sequence conservation and, as revealed by hydrogen-deuterium exchange studies, is also the most stable. Moreover, overexpression of PAQR3 suppressed LSCC cell proliferation and invasion. Evaluation of the complementary, radiographic, semiologic elements of ameloblastoma. The National Immunization Survey is a multistage, random-digit dialing survey designed to measure vaccination coverage estimates of US children aged 19 to 35 months old.

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Immunohistochemical deposition of NSE was not changed in the sublingual glands of irradiated rats. After collection using a novel massage technique, semen samples were examined microscopically to assess contamination and quality. Among older adults with hypertension, both SDH and ISH have similar associations with incident HF and cardiovascular mortality. Improved Photobactericidal Activity of Ultraviolet-A Light in Combination with Isomerizable p-Coumaric Acid Derivatives. The firing patterns of neurons contained enough information to discriminate the identity of the character, the action performed, and the particular conjunction of action and character. Though not conclusive, some in vitro models have shown that certain materials possessing antimicrobial characteristics may reduce the severity of lesion formation, suggesting possible pathways for developing new composite and adhesive materials for restorations with potentially enhanced longevity. New Caledonian representation of the cosmopolitan genus Oxyethira Eaton is reviewed, with the description of new species bringing to 26 the total for the genus on the island. Since the remaining three had near-normal platelet fibrinogen and all nine failed to aggregate it is improbable that the failure to adsorb fibrinogen is responsible for the defect in aggregation. Finally, a chaotic neural network is used as the node in two regular networks to show the effectiveness of the proposed criteria. Since microbes that co-exist with plants are known to have significant effects on their growth according to the previous studies for terrestrial plants, this study has attempted to understand the plant-microbial interactions of a duckweed, Lemna minor, focusing on the growth promotion/inhibition effects so as noroxin 400mg dosage to assess the possibility of accelerated duckweed production by modifying co-existing bacterial community.

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Varicose fibers and cells containing this neuropeptide were localized in the dorsal motor nucleus of the vagus (dmnX) and nucleus commissuralis. X-ray absorption fine structure studies demonstrated that the zinc is coordinated by 4 sulfur ligands. The results show that age and municipality of residence associated with non-attendance of mammographic screening. Increasing rates of antibiotic resistance are associated with worse clinical outcomes and greater healthcare costs. The risk of acute liver injury associated with the use of antibiotics--evaluating robustness of results in the pharmacoepidemiological research on outcomes of therapeutics cleocin dosage form by a European consortium (PROTECT) project. Extended work availability and its relation with start-of-day mood and cortisol. Esophageal perforation is an uncommon but catastrophic complication of resuscitation with the esophageal obturator airway. Analysis of heterogeneity in nonspecific PEGylation reactions of biomolecules. The image-based simulation may be a powerful noninvasive tool for preprocedural planning of ablation procedures to potentially reduce the procedure time and complication rates. Binding of radioiodinated GMP-140 to heparin-Matrex-Pel 102 beads was divalent cation-independent and was strongly inhibited by excess fluid phase GMP-140 and heparin and by other sulfated glycans such as fucoidin and dextran-sulfate.

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As a special class of phospholipids, peroxisome-derived lipids (PDLs) have been proved to be potential ligands of invariant natural killer T (iNKT) cells in recent studies. We performed a qualitative analysis of action plans formulated by Professional Advisory Committee (PAC) teams at 12 LTC homes in the intervention arm of the Vitamin D and Osteoporosis Study (ViDOS) in Ontario, Canada. Reconsolidation studies have led to the hypothesis that memory, when labile, would be modified in order to incorporate new information. The six main peaks obtained through LC-MS were identified as flavonoids. Genetic programming for evolving due-date assignment models in job shop environments. This finding is explained by ballistic-type ionic motion at shorter times and by the collective motion of ions in hydrophilic clusters. A significant positive correlation was found between negative symptoms and platelet monoamine oxidase (MAO) activity in unmedicated male, but not female, schizophrenic patients. A technique for rapid detection of proteinase inhibitors in fractions after liquid chromatography is described. When implementing additional positive and negative feed-back loops from proteins encoded by these genes, the system response acquires a bistable behavior. This study investigated the use of microendoscopic posterior decompression for the treatment of thoracic OLF.

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Risk factors for multifocal seizures were assessed using sensitivity and specificity analysis. Preventive health care in the future: government task or market activity?. Pregnancy-related osteoporosis may lead to fracture during vaginal delivery. Our findings are relevant to the inflammatory mechanisms involved in multiple sclerosis and may provide a basis for development of novel therapeutic targets of the disease. Sodium bentonite zithromax dosage pediatric chart , a common barrier material, was contacted with water and landfill leachate spiked with PFCs in batch adsorption tests to measure PFC adsorption. In conclusion, Ro 40-5967 has a long-lasting antihypertensive effect after once-daily administration.

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Clinical background, exercise parameters and the efficacy of antiarrhythmic drugs were compared among these 7 groups. We examined this possibility by comparing seasonal water use patterns in a mixed stand of chaparral dominated by four species of shrubs: Quercus durata, Heteromeles arbutifolia, Adenostoma fasciculatum, and Rhamnus californica. Moniliformin, deoxynivalenol, 3Acetyldeoxynivalenol and zearalenone - Mycotoxins associated with corn cob fusariosis in Poland. This result indicates that the strains persisted in pig farms, in wild life, or in the natural environment in this region. Sulpiride was administered in three different daily dosages (starting with 400, 800 or 1200 mg) according to a double blind randomized administration schedule. Although Drosophila is widely used as a model to study growth, the mechanisms underlying this male-female difference in size remain unclear. baumannii between January 2007 and June 2013 was retrieved using computerized hospital databases. THREE STUDIES MET OUR INCLUSION CRITERIA, DESCRIBING A DISTINCT STUDY POPULATION: primary THR, primary TKR and revision THR. Fundus examination showed subfoveal severe exudation with a posterior pole serous detachment.

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