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Metco (Metronidazole)
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Metco

Metco is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
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Also known as: Metronidazole

Description

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Metco. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Metco overdose, Metco infusion should be discontinued. Patients should be treated symptomatically.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Metco ER dosage information

Side effects

The most common side effects associated with Metco are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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The recent discovery of bacterial cell-penetrating effector proteins (CPEs) - with the prototype being the T3SS effector protein YopM - established a new class of autonomously translocating immunomodulatory proteins. Hence, it is thought that future exposure to wild-type virus or HBV vaccine will induce a protective secondary immune response. From the technical point of view, the two alternatives appear to be nearly equal. The cholesterol metabolism is essential for cancer cell proliferation. Self-reported functional status (P less than 0.01) and age (P less than 0.05) were significant predictors of change in level of care in a logistic regression analysis containing all predictor variables. The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss. Hyperspectral imaging is demonstrated to be an effective tool for nondestructive measurement of Pseudomonas in raw chicken breast fillets.

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The collaborative relationship among the CNS, health science librarian, and staff nurse effectively addresses a variety of barriers to EBP. Effects of selective alpha 1- and alpha 2-adrenoceptor agonists on the physiologic properties of rat left atria. The results are compared in detail with those expected under a gradient model proposed earlier to account for the phenotype. Furthermore, the reproducibility, specificity and so on were evaluated by clinical specimens of sperm. Vasopressin RNA in the neural lobe of the pituitary: dramatic accumulation in response to salt loading. Retinal mitochondria are dysfunctional in diabetes, and mitochondrial DNA (mtDNA) is damaged and its transcription is compromised. Development of a selective solid phase extraction method for nitro musk compounds in environmental waters using a molecularly imprinted sorbent. Three-dimensional measurements of the occlusal surfaces of upper molars in a Dutch population. The highly stimulatory effect of porphyrins on Bacteroides growth lead us to propose their use as a potential determinant of bacterial colonization. The cyclic AMP-responsive element modulator (CREM) gene encodes both activator and repressor isoforms that act as transcription factors to regulate spermiogenesis.

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Both gel-based (two-dimensional polyacrylamide gel electrophoresis) and gel-free (shotgun and quantitative) mass spectrometry approaches are discussed. Survey of the tooth extractions in the 4 years of operation of the University of Turin Dental Clinic. Clinical literature provides substantial information on the effects of chronic alcohol abuse on bone remodeling and related skeletal disease processes. We studied the relationship between hospital characteristics and special care nursery use and total length of stay among GDM deliveries. We extend the differential theory to anisotropic cylindrical structures with an arbitrary cross section. Nevertheless, simulated driving performance improved after temporal lobectomy. Moreover, the ways it is influenced by some important factors such as the wavelength of incident beam and the properties of scatterers and Kerr medium are discussed, and some important properties and relations are revealed. Ultra-low threshold avalanche gain from solar-blind photodetector based on graded-band-gap-cubic-MgZnO. After training, participants attempted to reproduce the tracks from memory. We also investigated the peripheral, topical, spinal, and supraspinal antinociceptive properties of NA-3,4-DCM and evaluated the involvement of the glutamatergic system on the antinociceptive effects of NA-3,4-DCM in mice.

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Eighty-one women with psychosis of schizophrenic or paranoid type participated in a double-blind comparison of melperone (300 mg daily) and thiothixene (30 mg daily). Our findings indicate that the family of depalmitoylation enzymes may be substantially broader than previously believed. In the Department of Pharmacy of Kyoto University Hospital, a manufacturing facility for sterile drugs was established, independent of existing manufacturing facilities. Here we further characterize the novel barrier promoting effects of Tys in cultured human pulmonary endothelial cells (EC). In the present study, the contribution of spinal Rac1 to peripheral inflammatory pain was studied. In our case, aneurysm at sinus of Valsalva was progressively enlarging and presented with complete heart block. Participation in a clinical trial is believed to benefit patients but little is known about the post-trial effects on routine hospital-based care.

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Chemical and structural similarities in wall polysaccharides of some Penicillium, Eupenicillium and Aspergillus species. These findings indicate that the Brattleboro rat expresses a vasopressin gene, but at a reduced level. These results demonstrate the sensitivity of gastric carcinoma to this drug combination. An inactivating, voltage-dependent K current was studied in isolation by inhibiting Ca-activated K currents with internal Ca chelators and external tetraethylammonium ions. Early and late germinating classes of seedlings of a population of Viola blanda were censused for three years. The current study tested the potential of pharmacological modulation of NMDAR activity through the obligatory co-agonist binding site, to suppress the initiation of SD, and modulate the effects of SD on dendritic spine morphology, in in vitro hippocampal slices.

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In vitro cytodestruction of human leukemic cells using murine monoclonal antibodies and human complement. Benzodiazepines are the agents of first choice, with a preference of short-acting drugs. Nucleic Acid Crystallography via Direct Selenium Derivatization: RNAs Modified with Se-Nucleobases. Radiation treatment for the initial cancer can result in moderately high doses to the contralateral breast, possibly contributing to this heightened risk. Amyotrophic lateral sclerosis: a phylogenetic disease of the corticomotoneuron?. Retinoid augmentation of bioactive interleukin-1 production by murine keratinocytes. When sex what is generic flomax is not on fire: a prospective multicentre study evaluating the short-term effects of radical resection of endometriosis on quality of sex life and dyspareunia. By putting just-in-time therapy within a complete theoretical and practical context, including the tunnel delivery strategy and the self-regulation perspective, we have contributed to an understanding of how multiple delivery strategies in eHealth interventions can be combined. Some problems with the concept of clinical significance are noted and a call for validity studies is made.

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Impact of postoperative prostate-specific antigen disease recurrence and the use of salvage therapy on the risk of death. Researchers and clinicians used content analysis of interview transcripts to identify symptoms in patient language. Although a rare clinical entity, this is the largest series of cryptophthalmos reported so far with a proposed classification scheme for the congenital symblepharon variant. Targeted therapy for gastric cancer: Current status and future directions (Review). We show that 91/130 is compromised in oligomerization but that it targets to the Golgi in a manner indistinguishable from wild-type GBF1 and that it rapidly exchanges between the cytosolic and membrane-bound pools. Vitellin was purified from eggs of the silkworm,Bombyx mori, by a new method in which vitellin was extracted from isolated yolk granules. Asymptotic and resampling strategies were utilized to assess the mediating roles of hope, optimism, general self-efficacy and resilience. This was a retrospective study involving analysis of medical files, radiographs and consultations relating to patients who underwent surgical correction of clubfoot. Glucose-6-phosphate dehydrogenase deficiency among malaria patients of Honduras: a descriptive study of archival blood samples.

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