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Simvastatinum (Simvastatin)

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Simvastatinum is a lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart problems in those at high risk. It is taken by mouth.

Other names for this medication:
Actalipid, Docsimvasta, Dosavastatin, Lipex, Lipinorm, Lodales, Normotherin, Simbastatin, Simgal, Simvastatin, Simvastatina, Simvastatinum, Simvofix, Sinvacor, Sivastin, Statinal, Vasilip, Zocord, Zorced, Zorstat, Zosta, Zostin, Zostine, Zovast, Zovastin, Zovatin, Zurocid

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Also known as: Simvastatin


Simvastatinum is an HMG-CoA reductase inhibitor. Simvastatinum is used to: reduce the risk of heart attack, stroke, and death due to coronary heart disease; reduce the risk of heart attack, stroke, blood vessel blockage, or chest pain caused by angina; low high cholesterol and triglycerides; increase high-density lipoprotein (HDL, "good") cholesterol levels. Simvastatinum is also known as Imvastatin, Simlup, Simcardis, Ranzolont, Simvador. Simvastatinum works by reducing the production of certain fatty substances in the body, including cholesterol. Generic name of Simvastatinum is Simvastatin. Brand name of Simvastatinum is Simvastatinum.


Take Simvastatinum orally. Take Simvastatinum with or without food. Do not use grapefruit or grapefruit juice while taking Simvastatinum. Eating grapefruit or drinking grapefruit juice may increase the amount of Simvastatinum in blood, what may increase the serious side effects. If you want to achieve most effective results do not stop taking Simvastatinum suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Simvastatinum are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Simvastatinum if you are allergic to simvastatin, if you are pregnant or breast-feeding, or if you have active liver disease.

The following drugs can increase your risk of serious muscle problems if you take them together with Simvastatinum. These drugs should not be used while you are taking Simvastatinum:

cyclosporine; danazol; gemfibrozil; nefazodone; an antibiotic - clarithromycin, erythromycin, telithromycin; antifungal medication - itraconazole, ketoconazole, posaconazole, voriconazole; hepatitis C medications - boceprevir, telaprevir; or HIV/AIDS medication - atazanavir, cobicistat (Stribild, Tybost), darunavir, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir.

Before you start taking Simvastatinum, tell your doctor if you are already using any of these other medicines:

lomitapide; or heart medication - amiodarone, amlodipine, diltiazem, dronedarone, ranolazine, verapamil.

To make sure Simvastatinum is safe for you, tell your doctor if you have:

history of liver disease; history of kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily.

Simvastatinum can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

FDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not take Simvastatinum if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking this medicine.

Simvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Simvastatinum.

Simvastatinum pregnancy and breastfeeding warnings (more detail)

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